7,321 results found
    1. Cell Biology

    The cell proliferation antigen Ki-67 organises heterochromatin

    Michal Sobecki et al.
    Antigen Ki-67, which is widely used as a cell proliferation marker, controls heterochromatin organisation and gene expression.
    1. Microbiology and Infectious Disease

    Infectious polymorphic toxins delivered by outer membrane exchange discriminate kin in myxobacteria

    Christopher N Vassallo et al.
    Serial cell-to-cell transfer of lipoprotein toxins by outer membrane exchange provides a potent platform for kin discrimination in Myxococcus xanthus.
    1. Structural Biology and Molecular Biophysics

    Kin discrimination in social yeast is mediated by cell surface receptors of the Flo11 adhesin family

    Stefan Brückner et al.
    Structural, biophysical and physiological analysis reveals how yeast cell surface adhesins evolved to confer self-nonself discrimination in single cells and whole populations.
    1. Structural Biology and Molecular Biophysics
    2. Cancer Biology

    The Ki-67 and RepoMan mitotic phosphatases assemble via an identical, yet novel mechanism

    Ganesan Senthil Kumar et al.
    Building on previous work (Booth et al, 2014), we show how two mitotic phosphatases are formed, how they are regulated by opposing kinases during the cell cycle and reveal a novel opportunity for the development of cancer therapeutics.
    1. Microbiology and Infectious Disease

    Kin cell lysis is a danger signal that activates antibacterial pathways of Pseudomonas aeruginosa

    Michele LeRoux et al.
    The death of bacterial kin cells releases a danger signal that activates a posttranscriptional response in surviving cells, resulting in the rapid elaboration of interbacterial competition factors.
    1. Structural Biology and Molecular Biophysics
    2. Human Biology and Medicine

    Connexin26 hemichannels with a mutation that causes KID syndrome in humans lack sensitivity to CO2

    Louise Meigh et al.
    Building on previous work (Meigh et al., 2013) we show that A88V, a mutation in connexin26 (Cx26) that causes Keratitis-Ichthyosis-Deafness (KID) syndrome in humans, is linked to a lack of sensitivity to CO2 by Cx26 hemichannels.
    1. Cell Biology

    Ki-67 is a PP1-interacting protein that organises the mitotic chromosome periphery

    Daniel G Booth et al.
    The mitotic chromosome periphery is organised by the PP1 binding protein Ki-67 and contributes to nucleolar re-activation upon mitotic exit.
    1. Neuroscience

    KIT ligand protects against both light-induced and genetic photoreceptor degeneration

    Huirong Li et al.
    A combination of in vitro and in vivo experiments demonstrate a cell-autonomous role of the KIT ligand/KIT signaling pathway in protecting retinal photoreceptor cells from environmentally or genetically caused degeneration.

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