The transcription machinery used to regulate gene expression and self-renewal in human embryonic stem cells is different from that found in other cells.

A combination of cellular, biochemical, genetic and genomic techniques have revealed a new molecular player in the production of fat cells in mice, which could improve our understanding of obesity.

The circadian clock in the model plant organism Arabidopsis thaliana is best described as a highly connected network made up of clock-regulated activators and repressors of transcription, rather than two coupled, repressor-based feedback loops.

Skin cells from a patient with retinitis pigmentosa have been used to generate induced pluripotent stem cells, which could potentially form the basis of new treatments for this disease.

A comprehensive study of human transcription factors reveals that a greater number of these proteins bind to methylated DNA sequences than previously thought.

Cells from vertebrate and invertebrate model systems can be reprogrammed into stem-like cells using mouse genes.

The differentiation decisions made by pluripotent cells depend on their exposure to appropriate extrinsic signals and also on morphogenetic events that control receptivity to those differentiation cues.

RNA binding is a key input of an active chromatin complex and maintenance of stem cell fate.

Schwann cell induced quiescence of mechanosensory progenitor cells is mediated by inhibition of Wnt/β-catenin signaling.