251 results found
    1. Medicine

    Insights from a Pan India Sero-Epidemiological survey (Phenome-India Cohort) for SARS-CoV2

    Salwa Naushin et al.
    Widespread asymptomatic SARS-CoV2 infection affected nearly 100 million Indians by September 2020 with a subsequent decline in new cases, which may be attributable to increased population immunity, albeit seeing reduced neutralization activity at 6 months this respite may be temporary.
    1. Medicine

    Asprosin-neutralizing antibodies as a treatment for metabolic syndrome

    Ila Mishra et al.
    Anti-asprosin monoclonal antibodies, a promising pharmacotherapy for the treatment of metabolic syndrome-associated hyperglycemia, obesity, and dyslipidemia.
    1. Neuroscience

    Impaired spatial learning and suppression of sharp wave ripples by cholinergic activation at the goal location

    Przemyslaw Jarzebowski et al.
    Elevated cholinergic activity disrupts offline hippocampal state and impairs memory formation highlighting the need for a precise timing of cholinergic activity in learning and memory.
    1. Cell Biology
    2. Computational and Systems Biology

    Quantifying absolute gene expression profiles reveals distinct regulation of central carbon metabolism genes in yeast

    Rosemary Yu et al.
    Global gene expression control mechanisms are modeled using a large dataset consisting of absolute-quantitative proteomics, transcriptomics, and partial metabolomics of Saccharomyces cerevisiae at a wide range of growth conditions.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    FRET-based dynamic structural biology: Challenges, perspectives and an appeal for open-science practices

    Eitan Lerner et al.
    A summary of the current “state-of-the-field” of single-molecule FRET used for probing biomolecular structural dynamics.
    1. Developmental Biology
    2. Physics of Living Systems

    From local resynchronization to global pattern recovery in the zebrafish segmentation clock

    Koichiro Uriu et al.
    Theory explains how transport of gene expression vortices by cell advection may cause intermingled defective and normal segments along the body axis during resynchronization experiments in the zebrafish segmentation clock.
    1. Neuroscience

    Functional reallocation of sensory processing resources caused by long-term neural adaptation to altered optics

    Antoine Barbot et al.
    Chronic exposure to poor optical quality causes a functional reallocation of sensory processing resources that favors perceptual information less affected by the eye's optics.
    1. Computational and Systems Biology
    2. Genetics and Genomics

    Alzheimer’s Disease: Exploring the origins of nucleation

    Katarzyna Marta Zoltowska, Lucía Chávez-Gutiérrez
    An approach called deep mutational scanning is improving our understanding of amyloid beta aggregation.
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