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TTC26/DYF13 is an intraflagellar transport protein required for transport of motility-related proteins into flagella
Hiroaki Ishikawa et al.
Loss of one protein from the intraflagellar transport complex leads to a defect in import of a specific sub-set of proteins into the flagellum.
Immunology and Inflammation
Pivotal role for skin transendothelial radio-resistant anti-inflammatory macrophages in tissue repair
Olga Barreiro et al.
A new type of skin perivascular macrophages with extramedullary origin, access to blood and exclusive anti-inflammatory reparative properties has been characterized.
Computational and Systems Biology
Physics of Living Systems
Persistence, period and precision of autonomous cellular oscillators from the zebrafish segmentation clock
Alexis B Webb et al.
Time-lapse recording and theoretical analysis of individual cells isolated from the zebrafish segmentation clock reveal that they behave as self-sustained, autonomous oscillators with distinctive noisy dynamics.
Developmental Biology and Stem Cells
Divergent mechanisms regulate conserved cardiopharyngeal development and gene expression in distantly related ascidians
Alberto Stolfi et al.
Embryos of distantly related sea squirt species are nearly identical but develop according to different gene regulatory mechanisms.
Tethering of an E3 ligase by PCM1 regulates the abundance of centrosomal KIAA0586/Talpid3 and promotes ciliogenesis
Lei Wang et al.
Ciliogenesis is regulated by a certain group of centriolar satellite proteins, among which an E3 ligase is tethered by PCM1 to maintain the normal level of pro-ciliogenic protein on centrioles.
Structural Biology and Molecular Biophysics
Systematic studies of all PIH proteins in zebrafish reveal their distinct roles in axonemal dynein assembly
Hiroshi Yamaguchi et al.
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