1,212 results found
    1. Computational and Systems Biology
    2. Neuroscience

    Multilayer brain networks can identify the epileptogenic zone and seizure dynamics

    Hossein Shahabi, Dileep R Nair, Richard M Leahy
    Aging and the duration of epilepsy can intensify the high-frequency desynchronization between the epileptogenic zone and the rest of the brain in early to mid-seizure.
    1. Plant Biology

    LEAFY maintains apical stem cell activity during shoot development in the fern Ceratopteris richardii 

    Andrew RG Plackett, Stephanie J Conway ... Verónica S Di Stilio
    Transgenic analysis reveals a role for LEAFY in ferns that supports a trajectory from general to floral meristem-specific function as land plants evolved.
    1. Ecology
    2. Evolutionary Biology

    Proteomics reveals synergy between biomass degrading enzymes and inorganic Fenton chemistry in leaf-cutting ant colonies

    Morten Schiøtt, Jacobus J Boomsma
    Leaf-cutting ants use their fecal fluid to vector enzymes produced by their fungal symbiont to degrade plant biomass with a combination of degradation enzymes and Fenton chemistry.
    1. Structural Biology and Molecular Biophysics

    How IGF-1 activates its receptor

    Jennifer M Kavran, Jacqueline M McCabe ... Daniel J Leahy
    Ligand binding to the ectodomain of the insulin-like growth factor receptor destabilises an autoinhibitory inter-subunit interaction, which allows the transmembrane domains to associate and the intracellular regions to autophosphorylate.
    1. Plant Biology

    Active suppression of a leaf meristem orchestrates determinate leaf growth

    John Paul Alvarez, Chihiro Furumizu ... John L Bowman
    A meristem acting at the margins of Arabidopsis leaves is suppressed by factors acting primarily in leaves and other determinate organs.
    1. Cell Biology

    Dopamine receptors reveal an essential role of IFT-B, KIF17, and Rab23 in delivering specific receptors to primary cilia

    Alison Leaf, Mark Von Zastrow
    The mechanism of signaling receptor delivery to primary cilia involves a specific cellular role of a Rab protein that is critical for vertebrate development.
    1. Plant Biology

    An oomycete effector subverts host vesicle trafficking to channel starvation-induced autophagy to the pathogen interface

    Pooja Pandey, Alexandre Y Leary ... Tolga O Bozkurt
    A pathogen effector mimics starvation-induced autophagy by subverting host endomembrane trafficking to stimulate biogenesis of autophagosomes around pathogen feeding sites, revealing how pathogens interlock distinct host compartments to facilitate infection.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Tubulin cofactors and Arl2 are cage-like chaperones that regulate the soluble αβ-tubulin pool for microtubule dynamics

    Stanley Nithianantham, Sinh Le ... Jawdat Al-Bassam
    Soluble αβ-tubulin assembly is regulated by a cage-like molecular complex containing tubulin cofactors and Arl2.
    1. Ecology
    2. Neuroscience

    Feeding-induced rearrangement of green leaf volatiles reduces moth oviposition

    Silke Allmann, Anna Späthe ... Bill S Hansson
    The ability of Manduca moths to recognize changes in the profile of volatile compounds released by plants being attacked by Manduca caterpillars allows them to lay their eggs on plants that are less likely to be attacked by insects and other predators, and to avoid competing against other caterpillars of the same species for resources.
    1. Developmental Biology

    Motor neurons are dispensable for the assembly of a sensorimotor circuit for gaze stabilization

    Dena Goldblatt, Basak Rosti ... David Schoppik
    An analysis of vestibular projection neurons lacking their motor neuron partners resolves outstanding controversies for whether and how motor neurons shape vestibulo-ocular reflex circuit assembly.

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