Cytosolic S100A8/A9 enhances Ca²⁺ availability at LFA-1 adhesion sites, facilitating neutrophil recruitment and extravasation by supporting proper integrin signaling and cytoskeletal rearrangement.

A hitherto unknown role of Piezo1 mechanosensors in chemotactic migration of human T cells is identified, linking focal adhesion formation to integrin recruitment.

A group of innate-like lymphocytes surveys the lymph node subcapsular sinus for bacterial and fungal invaders using a novel combination of chemoattractant and adhesion molecules.

Daughter-cell-associated factors and centrosome-based regulation is important in mitotic exit and spindle position checkpoint control.

The cell surface protein CD95 mediates neutrophil slow rolling and adhesion during inflammation.

Inhibition of the catalytic activity of the Zap70 kinase reveals that discrete TCR-regulated events control the remodelling of the actin cytoskeleton when the cytotoxic T cell interacts with its target.

By restricting actin polymerization to the perimeter of the immune synapse and promoting depolymerization, calcium influx drives centripetal actin flow, which confines CRAC channels and the endoplasmic reticulum to the synapse center.

Development of mouse thymocytes through the pre-TCR checkpoint requires WNK1 kinase signalling via the OXSR1 and STK39 kinases and the SLC12A2 ion co-transporter leading to MYC-dependent cell proliferation.

PP1-Bud14 is a novel Spindle Position Checkpoint component.

A MRI study of virally infected CNS demonstrates the utility of MRI in detecting the earliest pathological events and studying pathogen-specific T cells at the level of single cell as well as the therapeutic potential of antiviral T cells.