Secretion of the inflammatory cytokine TNF requires a protein called iTAP/FrmD8, which controls the cell surface stability of the TNF shedding machinery, iRhom2 and TACE/ADAM17.

Fission yeasts cells have about 190 cytokinesis nodes in a broad band at the equator which scales with cell size and most but not all nodes condense into the contractile ring.

CLR01 is a small molecule that could be an effective topical microbicide to eliminate HIV (and other enveloped viruses), and to antagonize host-encoded amyloid fibrils that promote HIV infection.

Cellular and vacuolar size expansion are coordinated.

Caenorhabditis elegans require a GPCR to recognize and rapidly escape from toxin-producing Streptomyces at their head or tail.

Mosquitoes may be likely to adapt to climate warming given their short life cycles and strong temperature sensitivity, but key data gaps identified here constrain current estimates of adaptive potential.

The presence of cenexin at the old centrosome imposes a functional asymmetry on the mitotic spindle that impacts chromosome alignment and segregation.

Bacteria release ATP as part of their attack in sepsis.

Deregulated cell fate specification pathways, including oncogenic Ras, cause activation of JNK-signaling at contact sites with wild type cells, which drives apoptosis and aberrant cell elimination in a contact-dependent manner.

A chemical probe was characterized for potency, selectivity, and ability to alter CARM1-dependent epigenetic plasticity against cancer cell invasion.