593 results found
    1. Epidemiology and Global Health

    Social contact patterns and implications for infectious disease transmission – a systematic review and meta-analysis of contact surveys

    Andria Mousa, Peter Winskill ... Charles Whittaker
    Differences in patterns of social contact between settings have consequences for the spread and transmission of respiratory pathogens and the effectiveness of different measures aimed at their control.
    1. Epidemiology and Global Health

    The impact of COVID-19 on cancer screening and treatment in older adults: The Multiethnic Cohort Study

    Victoria P Mak, Kami White ... Loic Le Marchand
    During the COVID-19 pandemic, cancer-related screening and healthcare practices varied (by age, race/ethnicity, education, and comorbidities), and considering these differences in high-risk individuals' monitoring is important as undiagnosed cases or poor prognosis may increase due to delayed screening/treatment.
    1. Computational and Systems Biology
    2. Medicine

    Identification of human glucocorticoid response markers using integrated multi-omic analysis from a randomized crossover trial

    Dimitrios Chantzichristos, Per-Arne Svensson ... Gudmundur Johannsson
    A human experimental model for physiological glucocorticoid exposure and glucocorticoid withdrawal identifies a multi-omic cluster, including microRNA miR-122-5p and metabolites, associated with glucocorticoid-responsive genes.
    1. Genetics and Genomics
    2. Stem Cells and Regenerative Medicine

    Multi-omic rejuvenation of human cells by maturation phase transient reprogramming

    Diljeet Gill, Aled Parry ... Wolf Reik
    Transiently reprogramming human fibroblasts up to the maturation phase rejuvenates cells according to several aging markers whilst enabling them to return to their original identity.
    1. Cell Biology
    2. Computational and Systems Biology

    Multi-omic analysis of bat versus human fibroblasts reveals altered central metabolism

    N Suhas Jagannathan, Javier Yu Peng Koh ... Lisa Tucker-Kellogg
    To investigate why bats are long-lived and cancer-resistant, multi-omic data from bat and human cells was analyzed using computational flux modeling, suggesting dysregulation of succinate-fumarate dynamics and an ischemic-like basal metabolism in bat cells.
    1. Cancer Biology
    2. Cell Biology

    CYRI-B-mediated macropinocytosis drives metastasis via lysophosphatidic acid receptor uptake

    Savvas Nikolaou, Amelie Juin ... Laura M Machesky
    Macropinocytosis of the signalling receptor LPAR1, by an actin and CYRI-B-dependent mechanism, impacts on progression and spread of pancreatic cancer in a mouse model.
    1. Cell Biology
    2. Developmental Biology

    Cellular aspect ratio and cell division mechanics underlie the patterning of cell progeny in diverse mammalian epithelia

    Kara L McKinley, Nico Stuurman ... Ronald D Vale
    The process of cytokinesis can allow cell lineages to intermix in mammalian epithelia, and cellular aspect ratio is a critical modulator of this behavior.
    1. Epidemiology and Global Health

    Quantification of impact of COVID-19 pandemic on cancer screening programmes – a case study from Argentina, Bangladesh, Colombia, Morocco, Sri Lanka, and Thailand

    Eric Lucas, Raul Murillo ... Partha Basu
    Well-coordinated, decisive, and collective actions remain critical to make screening programmes more equitable and resilient in the face of natural and geo-political calamities.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    A Ras-like domain in the light intermediate chain bridges the dynein motor to a cargo-binding region

    Courtney M Schroeder, Jonathan ML Ostrem ... Ronald D Vale
    The dynein light intermediate chain is a member of the G protein superfamily and links the motor to several intracellular cargo adaptors.
    1. Epidemiology and Global Health

    Design of the HPV-automated visual evaluation (PAVE) study: Validating a novel cervical screening strategy

    Silvia de Sanjosé, Rebecca B Perkins ... Mark Schiffman
    The PAVE strategy aims to provide a cost-effective, high quality ‘Screen-Triage-Treat’ approach for cervical cancer screening to save many lives.

Refine your results by:

Type
Research categories