Browse the search results

Page 2 of 10
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Within-host evolutionary dynamics of seasonal and pandemic human influenza A viruses in young children

    Alvin X Han, Zandra C Felix Garza ... Colin A Russell
    The longer duration of seasonal influenza virus infection in young children may provide opportunities for within-host evolution as a result of maintenance of genetic diversity through mutation-selection balance.
    1. Neuroscience

    Sensorimotor pathway controlling stopping behavior during chemotaxis in the Drosophila melanogaster larva

    Ibrahim Tastekin, Avinash Khandelwal ... Matthieu Louis
    The reconstruction of a sensorimotor pathway from the olfactory-sensory neurons down to the pre-motor system reveals a descending neuron that plays a critical role in the organization of larval chemotaxis.
    1. Neuroscience

    A resource for the Drosophila antennal lobe provided by the connectome of glomerulus VA1v

    Jane Anne Horne, Carlie Langille ... Ian A Meinertzhagen
    FIB-SEM is used to identify comprehensively and reconstruct 192 neurons and their complete connectome for glomerulus VA1v of the Drosophila antennal lobe, in particular to reconstruct its local interneurons.
    1. Ecology
    2. Evolutionary Biology

    Host-parasite coevolution promotes innovation through deformations in fitness landscapes

    Animesh Gupta, Luis Zaman ... Justin R Meyer
    An interdisciplinary approach combining high throughput genotype-to-phenotype mapping, population genetic simulations, and experimental evolution provides an answer to the question of how populations evolve new functions by providing tests of the role antagonistic coevolution plays in pressuring populations to innovate.
    1. Ecology
    2. Evolutionary Biology

    Windborne migration amplifies insect-mediated pollination services

    Huiru Jia et al.
    Delineating Episyrphus balteatus transregional movements and pollination networks advance a deep understanding of its migration ecology and facilitate the design of targeted strategies to conserve and enhance its ecosystem services.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Drosophila SUMM4 complex couples insulator function and DNA replication control

    Evgeniya N Andreyeva, Alexander V Emelyanov ... Dmitry V Fyodorov
    Biochemical and biological characterization of insulator complex SUMM4 reveals that, in addition to disrupting enhancer–promoter interactions and establishing chromatin barriers, it functions to delay DNA replication, thus implicating architectural proteins in shaping spatiotemporal patterns of replication.
    1. Developmental Biology

    Optogenetic control of gut bacterial metabolism to promote longevity

    Lucas A Hartsough, Mooncheol Park ... Jeffrey J Tabor
    Light controls can fine tune microbiome–host interaction to qualitatively regulate host longevity with temporal and spatial precision.
    1. Biochemistry and Chemical Biology
    2. Chromosomes and Gene Expression

    Chemical perturbation of an intrinsically disordered region of TFIID distinguishes two modes of transcription initiation

    Zhengjian Zhang, Zarko Boskovic ... Robert Tjian
    An inorganic tin oxochloride cluster specifically binds to an intrinsically disordered, histidine-rich, low complexity protein region and arrests de novo transcription initiation without affecting reinitiation.
    1. Computational and Systems Biology
    2. Developmental Biology

    Vascular dimorphism ensured by regulated proteoglycan dynamics favors rapid umbilical artery closure at birth

    Sumeda Nandadasa, Jason M Szafron ... Suneel S Apte
    Morphologic, molecular, biomechanical and computational analyses show that the specialized extracellular matrix architecture of the umbilical artery contributes to its rapid closure at birth and regulates smooth muscle cell differentiation.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Radiocarbon and genomic evidence for the survival of Equus Sussemionus until the late Holocene

    Dawei Cai, Siqi Zhu ... Yu Jiang
    The first nuclear genomes of the Equus (Sussemionus) ovodovi enable us to reconstruct the speciation and extinction trajectory of this lineage.