People’s neural activity travels between a small number of brain states based on what they are thinking and paying attention to.

Confidence-dependent reinforcement learning is active and produces trial-to-trial choice updating even in well-learned perceptual decisions without explicit reward biases, across species and sensory modalities.

A high-phytate-low Ca²⁺ diet causes crystal nephropathies, renal phosphate wasting, and bone disease in rats, whereas high Ca²⁺ intake ameliorates the detrimental effects of a high-phytate diet.

Tracking of all cells in intestinal organoids crypts to fully reconstruct cell lineages reveals that proliferative behavior is highly symmetric between sisters cells, while simulations show that this observed symmetry minimizes random fluctuations in cell proliferation, thereby ensuring homeostasis.

The early influence of the breakdown of both hippocampal structural network and angular gyrus-seeded default mode metabolism network on memory performance underscore the importance of early intervention in preclinical Alzheimer’s disease.

The transcription machinery is required for the disassembly of the promoter-proximal H2A.Z nucleosome, contributing to the constitutive histone turnover at yeast promoters.

Epigenetic determination of tissue of origin of genetically classified subsets of plasma DNA molecules enhances transplantation monitoring and cancer testing.

Developmental defects of the cochlea caused by dysregulation of sonic hedgehog signaling are the potential etiology for hearing loss in a group of ciliopathies with defective ciliogenesis.

Recurrent neural networks trained to navigate and infer latent states exhibit strikingly similar remapping patterns to those observed in navigational brain areas, inspiring new analyses of published data and suggesting a possible function for spontaneous remapping to support context-dependent navigation.

Pervasive ‘futile cycling’ by chromatin-modifying factors suggests a mechanism for creating new links in gene regulatory networks.