391 results found
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    EDF1 coordinates cellular responses to ribosome collisions

    Niladri K Sinha et al.
    Endothelial Differentiation Factor 1 (EDF1) plays a critical role in driving mRNA-specific quality control and global transcriptional responses in response to ribosome collisions.
    1. Ecology
    2. Neuroscience

    Genetic variation in the social environment affects behavioral phenotypes of oxytocin receptor mutants in zebrafish

    Diogo Ribeiro et al.
    Individual social behavior results from the interaction between the individuals own oxytocin receptor genotype and the oxytocin receptor genotypes of other individuals present in its social environment.
    1. Computational and Systems Biology
    2. Ecology

    Combining agent-based, trait-based and demographic approaches to model coral-community dynamics

    Bruno Sylvain Carturan et al.
    A new agent-based model enables predicting how coral species richness and functional diversity affect the functioning and resilience of coral reef ecosystems.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Chemical and structural investigation of the paroxetine-human serotonin transporter complex

    Jonathan A Coleman et al.
    Structural and biochemical analysis of the mechanism of paroxetine binding to the serotonin transporter provides a framework for transporter inhibition and design of small-molecule inhibitors.
    1. Developmental Biology
    2. Neuroscience

    The role of the NMD factor UPF3B in olfactory sensory neurons

    Kun Tan et al.
    The nonsense-mediated RNA decay (NMD) branch-specific factor UPF3B influences olfactory sensory neuron cell populations, the olfactory receptor repertoire, and antimicrobial gene expression.
    1. Neuroscience

    Altered functional connectivity during speech perception in congenital amusia

    Kyle Jasmin et al.
    Individuals with amusia, who have unreliable pitch processing, show decreased functional connectivity between right auditory and left language-related cortex during speech perception, demonstrating a neural basis for compensatory dimensional weighting.
    1. Neuroscience

    Learning prediction error neurons in a canonical interneuron circuit

    Loreen Hertäg, Henning Sprekeler
    The formation and refinement of prediction error circuits relies on an experience-dependent balance of excitation and inhibition in canonical microcircuits.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Measuring protein stability in the GroEL chaperonin cage reveals massive destabilization

    Ilia Korobko et al.
    Protein stability in the cage formed by the chaperonin GroEL and its cofactor GroES is reduced by more than 5 kcal mol-1 relative to that in bulk solution.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Alternative splicing of coq-2 controls the levels of rhodoquinone in animals

    June H Tan et al.
    The switch from ubiquinone to rhodoquinone synthesis that is required for parasitic helminths to survive in anaerobic host tissues is due to alternative splicing of polyprenyltransferase COQ-2.
    1. Developmental Biology
    2. Genetics and Genomics

    An atlas of cell types in the mouse epididymis and vas deferens

    Vera D Rinaldi et al.
    A systematic survey of the epididymis identifies the cell types involved in post-testicular maturation of sperm.

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