Epigenome and Mitochondrial Barcode of Lineage from Endogenous Mutations (EMBLEM) enable tracking cell lineage in combination with chromatin profile in ATAC-seq data.
TBX5 lineage tracing and high resolution single cell transcriptomics uncover the predominance of first heart field development during human-induced pluripotent stem cell cardiac differentiation.
Maaike Welling, Manuel Alexander Mohr ... Periklis Pantazis
Primed Track is an image analysis tool that allows for computational correction of drifting specimen to enable accurate lineage tracing of mammalian pre-implantation development even for larger imaging time intervals.
Infrared laser-mediated gene induction microscopy enables precise single-cell labeling in various tissues of zebrafish, and in vivo visualized single-cell lineage tracing reveals the lineage heterogeneity in hematopoietic endothelial cells.
A combination of live cell tracking, cell-lineage tracing and machine learning shows that injured sensory organs repair accurately regardless of the extent of damage.
Genetic lineage tracing approach combined with live imaging visualized the functional stem cell activity of Doublecortin-like kinase 1+ cells within pancreatic cancer in vivo.
Phoebe M Kirkwood, Douglas A Gibson ... Philippa TK Saunders
In a mouse model of menstruation stromal cells respond to breakdown of the tissue by changing their identity to become epithelial cells that are incorporated into the luminal epithelium which is rapidly 'healed' without scarring.
Grant Parker Flowers, Lucas D Sanor, Craig M Crews
CRISPR-based lineage tracing in the axolotl shows that regenerated limbs are composed of the same cell lineages in the same frequencies as those that gave rise to the original limb.
Quantitative analyses of multi-dimensional microscopy datasets with a new Fiji/ImageJ plugin for cell tracking reveal the lineage restrictions and morphogenetic cellular behaviors underlying embryonic limb outgrowth in the direct developing crustacean Parhyale hawaiensis.