363 results found
    1. Neuroscience

    The connectome of the adult Drosophila mushroom body provides insights into function

    Feng Li, Jack W Lindsey ... Gerald M Rubin
    Analysis of neuronal circuit architecture provides mechanistic insights into what an adult fly can learn, remember, and use to guide its behavior.
    1. Developmental Biology
    2. Neuroscience

    Diversification of multipotential postmitotic mouse retinal ganglion cell precursors into discrete types

    Karthik Shekhar, Irene E Whitney ... Joshua R Sanes
    Single-cell transcriptomic analysis of developing retinal ganglion cells in mice suggests that their diversification into 45 discrete types occurs via the gradual restriction of multipotential precursors.
    1. Neuroscience

    Cerebellar learning using perturbations

    Guy Bouvier, Johnatan Aljadeff ... Boris Barbour
    A proposal for a complete cellular/network implementation of trial-and-error motor learning in the olivo-cerebellar system.
    1. Neuroscience

    Neural Correlates and Reinstatement of Recent and Remote Memory: A Comparison Between Children and Young Adults

    Iryna Schommartz, Philip F Lembcke ... Yee Lee Shing
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete
    1. Cell Biology
    2. Neuroscience

    APOE expression and secretion are modulated by mitochondrial dysfunction

    Meghan E Wynne, Oluwaseun Ogunbona ... Victor Faundez
    Current models of Alzheimer's disease that put mitochondria as an endpoint of disease should be reconsidered because genetic defects affecting mitochondria by themselves can also regulate Alzheimer’s disease risk factor apolipoprotein E (APOE) expression and secretion.
    1. Neuroscience

    Parallel reconstruction of the excitatory and inhibitory inputs received by single neurons reveals the synaptic basis of recurrent spiking

    Julian Bartram, Felix Franke ... Andreas Hierlemann
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    • Convincing
    1. Immunology and Inflammation
    2. Neuroscience

    A microglia clonal inflammatory disorder in Alzheimer’s Disease

    Rocio Vicario, Stamatina Fragkogianni ... Frederic Geissmann
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Neuroscience

    Brain-imaging evidence for compression of binary sound sequences in human memory

    Fosca Al Roumi, Samuel Planton ... Stanislas Dehaene
    Humans memorize structured sound sequences using a language-of-thought compression algorithm.
    1. Neuroscience

    Reward contingency gates selective cholinergic suppression of amygdala neurons

    Eyal Y Kimchi, Anthony Burgos-Robles ... Kay M Tye
    Electrophysiological recordings and optogenetic manipulations revealed the distinct roles that acetylcholine can have on the amygdala and prefrontal cortex in a Window of Opportunity Task.
    1. Neuroscience

    Instructions and experiential learning have similar impacts on pain and pain-related brain responses but produce dissociations in value-based reversal learning

    Lauren Y Atlas, Troy C Dildine ... Daniel S Pine
    Combining computational models with FMRI in humans during pain reversal learning reveals parallel pain modulatory brain circuits that differ in their flexibility and sensitivity to instructions.

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