Karthik Shekhar, Irene E Whitney ... Joshua R Sanes
Single-cell transcriptomic analysis of developing retinal ganglion cells in mice suggests that their diversification into 45 discrete types occurs via the gradual restriction of multipotential precursors.
Meghan E Wynne, Oluwaseun Ogunbona ... Victor Faundez
Current models of Alzheimer's disease that put mitochondria as an endpoint of disease should be reconsidered because genetic defects affecting mitochondria by themselves can also regulate Alzheimer’s disease risk factor apolipoprotein E (APOE) expression and secretion.
Eyal Y Kimchi, Anthony Burgos-Robles ... Kay M Tye
Electrophysiological recordings and optogenetic manipulations revealed the distinct roles that acetylcholine can have on the amygdala and prefrontal cortex in a Window of Opportunity Task.
Combining computational models with FMRI in humans during pain reversal learning reveals parallel pain modulatory brain circuits that differ in their flexibility and sensitivity to instructions.