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The Chip/LDB-SSDP complex integrates multiple signals to render TCF/LEF enhancers Wnt responsive.

The identification of key determinants of LSC “stemness” and LSC differentiation that is reversible through an epigenetic mechanism may have considerable implications in understanding leukemia and designing effective therapies.

The aldehyde 4-hydroxy-2-nonenal is a novel component of the host antimicrobial reactive oxygen burst, and the bacterium Listeria monocytogenes encodes genes specifically for its detoxification.

Neural substrates of objective vs. subjective memory states can be distinguished, including their role in supporting decisions aimed at optimizing performance.

A new genomic method called MChIP-C measures H3K4me3-associated chromatin interactions with extremely high resolution and sensitivity, detecting interactions in over 60% of functionally verified enhancer-promoter pairs.

Linguistic features are encoded more strongly during language comprehension than when comprehension is absent, and high word entropy (less constraining context) enhances the encoding of lower-level acoustic and linguistic features while low word entropy suppresses it.

Fluctuations of spectral power in large-scale cortical networks shape behavior in a perceptual decision-making task through arousal-linked and arousal-independent mechanisms.

A simulation study is used to demonstrate how mistakes in identifying the experimental unit and the unit of analysis can lead to incorrect analyses and inappropriate inferences when reporting research studies.

Epigenetic clocks are an accurate measure of biological aging and 'tick' slower in male sheep that are castrated.

An analysis of more than 70,000 journal articles, including 5405 that were first released as a preprint on bioRxiv, shows that articles with a preprint received 49% more attention and 36% more citations than articles without one.