27 results found
    1. Microbiology and Infectious Disease

    Population structuring of multi-copy, antigen-encoding genes in Plasmodium falciparum

    Yael Artzy-Randrup, Mary M Rorick ... Mercedes Pascual
    Mathematical modeling shows that local populations of the malaria parasite self-organize into a limited number of transient but distinct strains through competition for hosts in immunity space.
    1. Ecology
    2. Chromosomes and Gene Expression

    Emerging Technology: Concerning RNA-guided gene drives for the alteration of wild populations

    Kevin M Esvelt, Andrea L Smidler ... George M Church
    Combining CRISPR/Cas9 genome editing with gene drives may enable scientists to reversibly edit the genomes of diverse wild populations, an advance that could help eliminate diseases, support sustainable agriculture, and control invasive species.
    1. Ecology
    Deer mouse illustration

    The Natural History of Model Organisms: Peromyscus mice as a model for studying natural variation

    Nicole L Bedford, Hopi E Hoekstra
    The deer mouse (Peromyscus) has emerged as a model system for studying many aspects of biology, supported by extensive historical knowledge of its fascinating and varied natural history.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Acquisition of exogenous haem is essential for tick reproduction

    Jan Perner, Roman Sobotka ... Petr Kopacek
    The lack of haem biosynthetic and degradative pathways in ticks offers new strategies to combat these parasites.
    1. Structural Biology and Molecular Biophysics
    2. Microbiology and Infectious Disease

    Extended low-resolution structure of a Leptospira antigen offers high bactericidal antibody accessibility amenable to vaccine design

    Ching-Lin Hsieh, Christopher P Ptak ... Yung-Fu Chang
    The antibody accessibility of the leptospiral surface protein, LigB, provides a guide for the rational design of improved recombinant chimeric vaccine antigens displayed on a single domain scaffold.
    1. Ecology
    2. Epidemiology and Global Health

    Ecological multiplex interactions determine the role of species for parasite spread amplification

    Massimo Stella, Sanja Selakovic ... Cecilia S Andreazzi
    Predators may amplify multiple-host parasite spreading in systems with multiple transmission routes.
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    Structural insights into flagellar stator–rotor interactions

    Yunjie Chang, Ki Hwan Moon ... Jun Liu
    In situ structural analysis of bacterial flagellar motor in the Lyme disease spirochete reveals novel conformational change driven by proton motive force.
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    An asymmetric sheath controls flagellar supercoiling and motility in the leptospira spirochete

    Kimberley H Gibson, Felipe Trajtenberg ... Charles Vaughn Sindelar
    The corkscrew-like motility of Spirochete bacteria is enabled by a unique, asymmetrically constructed flagellum that wraps around the cell body within the periplasm.
    1. Ecology
    2. Evolutionary Biology
    House sparrow illustration

    The Natural History of Model Organisms: The house sparrow in the service of basic and applied biology

    Haley E Hanson, Noreen S Mathews ... Lynn B Martin
    The house sparrow, one of the most ubiquitous birds in the world, is now used extensively in studies across disciplines in the life sciences.
    1. Immunology and Inflammation

    Human Fcγ-receptor IIb modulates pathogen-specific versus self-reactive antibody responses in lyme arthritis

    Heike Danzer, Joachim Glaesner ... Falk Nimmerjahn
    In the absence of human FcgRIIb function, an infection with Borrelia burgdorferi triggers enhanced autoreactive immune responses in humanized mice in vivo.

Refine your results by:

Type
Research categories