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    1. Biochemistry and Chemical Biology

    Nuclear bodies protect phase separated proteins from degradation in stressed proteome

    Kwan Ho Jung, Jiarui Sun ... Xin Zhang
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Incomplete
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    The fate of pyruvate dictates cell growth by modulating cellular redox potential

    Ashish G Toshniwal, Geanette Lam ... Jared Rutter
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Neuroscience

    Adaptive chunking improves effective working memory capacity in a prefrontal cortex and basal ganglia circuit

    Aneri V Soni, Michael J Frank
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Structural Biology and Molecular Biophysics

    Targeted anticancer pre-vinylsulfone covalent inhibitors of carbonic anhydrase IX

    Aivaras Vaškevičius, Denis Baronas ... Daumantas Matulis
    A series of compounds were synthesized and demonstrated to form a specific covalent bond with His64 of CAIX, an anticancer target, a strategy applicable to any drug design project.
    1. Cell Biology

    Oxidized low-density lipoprotein potentiates angiotensin II-induced Gq activation through the AT1-LOX1 receptor complex: Implications for renal dysfunction

    Jittoku Ihara, Yibin Huang ... Koichi Yamamoto
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Solid
    1. Neuroscience

    A multiplex of connectome trajectories enables several connectivity patterns in parallel

    Parham Mostame, Jonathan Wirsich ... Sepideh Sadaghiani
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Incomplete
    1. Neuroscience

    Restoration of locomotor function following stimulation of the A13 region in Parkinson’s mouse models

    Linda H Kim, Adam Lognon ... Patrick J. Whelan
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    • Incomplete
    1. Immunology and Inflammation
    2. Neuroscience

    A microglia clonal inflammatory disorder in Alzheimer’s Disease

    Rocio Vicario, Stamatina Fragkogianni ... Frederic Geissmann
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Developmental Biology

    A single-cell atlas of spatial and temporal gene expression in the mouse cranial neural plate

    Eric R Brooks, Andrew R Moorman ... Jennifer A Zallen
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Computational and Systems Biology
    2. Immunology and Inflammation

    Dynamically linking influenza virus infection kinetics, lung injury, inflammation, and disease severity

    Margaret A Myers, Amanda P Smith ... Amber M Smith
    Important nonlinear links between infection, inflammation, and disease severity were revealed using experimentally validated mathematical models.
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