A new nomenclature convention for mammalian cell types utilizing shared taxonomies and quantitative cell features is applied to high-quality, open data from the mouse and human brain.
New experiments and theory reveal how the ability to see image details depends upon photoreceptor function and eye movements, and how fruit flies (Drosophila) see spatial details beyond the optical limit of their compound eyes.
Dylan H Morris, Velislava N Petrova ... Colin A Russell
Despite the virus' error prone polymerase, influenza virus antigenic evolution is rare, even in previously immune hosts, virus replication occurs before producing new antibodies.
Bacterial CRISPR immunity tracks phage mutations, creating immune diversity in bacterial populations that parallels phage genetic diversity and patterns of phage evolution that are determined by the type and degree of immune cross-reactivity in the CRISPR system.
Valentina Baldazzi, Delphine Ropers ... Hidde de Jong
A coarse-grained model of microbial growth coupling fluxes of carbon and energy shows that resource allocation is a major explanatory factor of the observed variability of growth rates and growth yields across different bacterial strains.
A new deep-learning software toolkit with general-purpose methods for quickly and reliably measuring the full body posture of animals directly from images or videos without physical markers.
Observations of ant excavation from a confining corral, along with theoretical models and synthetic robot experiments show the emergence of cooperation induced by pheromones in a malleable environment that is moulded by and moulds collective behavior.
The combination of statistical inference and perturbation experiments reveals that trans-generational inheritance of cell size and cell-cycle speed, coupled through a minimum-size checkpoint, shapes paradoxical cell-cycle correlations in lineage trees.
Using unique data from five longitudinal UK birth cohorts, four distinct subsets of genetic variants were identified as differentially associated across wheezing phenotypes from infancy to adolescence with little evidence of genetic associations spanning across different phenotypes.
