Molecular mechanisms reveal that human cytomegalovirus has evolved to deploy two individual glycoproteins working in synergy to efficiently evade antibody-mediated immunity mediated by Fc-gamma receptors.
Specific human mitofusin 2 mutations induce selective upper body obesity with suppressed leptin expression and severe adipose mitochondrial dysfunction.
For the first time in a mosquito species an initial Y chromosome signal has been shown to regulate dosage compensation by increasing X chromosome gene expression.
William S Kruesi, Leighton J Core ... Barbara J Meyer
C. elegans equalizes the expression of X-chromosome genes between the sexes by reducing the recruitment of RNA polymerase II to promoters of X-linked genes in hermaphrodites, using a chromosome-restructuring complex called condensin.
The consolidation of newly acquired motor skills induces a functional reorganization of sequential information representations within secondary motor cortex, basal ganglia and hippocampus.
Non-REM sleep is essential in the restoration of initial motor memory trace and gradual reorganization of newly-learned information underlying human procedural memory consolidation.
Susanne U Franssen, Caroline Durrant ... James A Cotton
Genomic data for the parasites that cause visceral leishmaniasis provides the first global picture of the diversity and evolution of the pathogen and the epidemiology of this fatal tropical disease.
James R Partridge, Laura A Lavery ... David A Agard
Cytosolic and organellar Hsp90s from higher eukaryotes have evolved a variable, and environmentally responsive N-terminal extension to regulate their activity.
Maternal CLAMP functions as a novel pioneer transcription factor to open chromatin and plays a targeted yet essential role in Drosophila zygotic genome activation.
