444 results found
    1. Epidemiology and Global Health

    A century of trends in adult human height

    NCD Risk Factor Collaboration (NCD-RisC)
    Height in early adulthood is an indicator that integrates across different dimensions of sustainable human development with links to health and longevity, nutrition, education and economic productivity.
    1. Microbiology and Infectious Disease

    Functional insights from a surface antigen mRNA-bound proteome

    Larissa Melo do Nascimento, Franziska Egler ... Esteban Erben
    A robust procedure to purify mRNAs and their associated proteins identify CFB2 as the critical protein that binds and influences the fate of the main virulence factor in Trypanosoma brucei.
    1. Chromosomes and Gene Expression

    Chromosome structure in Drosophila is determined by boundary pairing not loop extrusion

    Xinyang Bing, Wenfan Ke ... James B Jaynes
    Boundary:boundary pairing interactions drive TAD formation in Drosophila.
    1. Developmental Biology
    2. Neuroscience

    Neuronal temperature perception induces specific defenses that enable C. elegans to cope with the enhanced reactivity of hydrogen peroxide at high temperature

    Francesco A Servello, Rute Fernandes ... Javier Apfeld
    C. elegans nematodes can assess faithfully the threat that H2O2 poses by coupling the induction of their H2O2 defenses to the perception of high temperature—an inherent enhancer of the reactivity of H2O2.
    1. Ecology
    2. Plant Biology

    A dynamic rhizosphere interplay between tree roots and soil bacteria under drought stress

    Yaara Oppenheimer-Shaanan, Gilad Jakoby ... Tamir Klein
    Increased root exudation rate under combined drought and bacterial inoculation and bacterial growth stimulation by specific exudation metabolites support the idea of root recruitment of beneficial bacteria, especially under water stress.
    1. Cell Biology
    2. Developmental Biology

    Mitochondrial fusion is required for spermatogonial differentiation and meiosis

    Grigor Varuzhanyan, Rebecca Rojansky ... David C Chan
    Mitochondrial fusion enables a metabolic transition during spermatogenesis.
    1. Cell Biology

    Modular, cascade-like transcriptional program of regeneration in Stentor

    Pranidhi Sood, Athena Lin ... Wallace F Marshall
    Regeneration of single Stentor coeruleus cells is accompanied by a program of gene expression that can be decomposed into distinct modules, showing a cascade-like organization, and involving genes with conserved function in development and cell cycle control.
    1. Biochemistry and Chemical Biology
    2. Computational and Systems Biology

    SIMMER employs similarity algorithms to accurately identify human gut microbiome species and enzymes capable of known chemical transformations

    Annamarie E Bustion, Renuka R Nayak ... Katherine S Pollard
    Computational reaction representations and profile hidden Markov model searches of metagenomics databases can be harnessed to accurately predict bacterial species and enzyme sequences responsible for biotransformations in the human gut microbiome.
    1. Biochemistry and Chemical Biology

    High-throughput proteomics of nanogram-scale samples with Zeno SWATH MS

    Ziyue Wang, Michael Mülleder ... Markus Ralser
    Zeno SWATH MS, a novel data-independent acquisition technique in proteomics, which by facilitating sensitive detection in high-throughput experiments with low sample amounts, mitigates current bottlenecks of high-throughput proteomics.
    1. Computational and Systems Biology
    2. Genetics and Genomics

    Global donor and acceptor splicing site kinetics in human cells

    Leonhard Wachutka, Livia Caizzi ... Patrick Cramer
    Transient transcriptome sequencing and kinetic modeling suggest how the kinetics and yield of RNA splicing are encoded in the human genome.

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