203 results found
    1. Neuroscience

    Neural representation of newly instructed rule identities during early implementation trials

    Hannes Ruge et al.
    Ventro-lateral prefrontal cortex codes novel rules starting from their first-time implementation right after instruction while early consolidation is channeled through increasing cooperation with the anterior striatum.
    1. Neuroscience

    Empathic pain evoked by sensory and emotional-communicative cues share common and process-specific neural representations

    Feng Zhou et al.
    Machine learning analyses reveal that the observation of acute pain inflictions and facial expressions of pain evoke shared pain-specific neural representations.
    1. Neuroscience

    Successful retrieval of competing spatial environments in humans involves hippocampal pattern separation mechanisms

    Colin T Kyle et al.
    Functional magnetic resonance imaging and multivariate pattern analysis reveal remapping-like behavior during successful retrieval of competing environments, while unsuccessful retrieval is accompanied by reinstatement of interfering representations.
    1. Neuroscience

    The dorsomedial prefrontal cortex computes task-invariant relative subjective value for self and other

    Matthew Piva et al.
    Activity in the dorsomedial prefrontal cortex encodes relative subjective value in a common neural code across decision-making for self and other and across tasks with divergent cognitive requirements.
    1. Neuroscience

    Role of matrix metalloproteinase-9 in neurodevelopmental deficits and experience-dependent plasticity in Xenopus laevis

    Sayali V Gore et al.
    Chronic dysregulation of matrix-metalloproteinase 9, which is associated with some neurodevelopmental disorders, leads to local hyperconnectivity in the developing brain, resulting in altered sensory processing and increased seizure susceptibility.
    1. Biochemistry and Chemical Biology
    2. Genetics and Genomics

    Discovery of a metabolic alternative to the classical mevalonate pathway

    Nikki Dellas et al.
    A combination of phylogenetic and biochemical analyses suggest that some unexpected variations in the synthesis of isoprenoids may be widespread across all three domains of life.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Evolutionary genomics of epidemic visceral leishmaniasis in the Indian subcontinent

    Hideo Imamura et al.
    Genome sequencing reveals the evolution and epidemiology of Leishmania donovani in the Indian subcontinent, where epidemics have caused up to 30,000 deaths per year.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Protein translocation channel of mitochondrial inner membrane and matrix-exposed import motor communicate via two-domain coupling protein

    Rupa Banerjee et al.
    Two domains of the peripheral membrane protein Tim44 interact with two different sectors of a translocase to coordinate the translocation of proteins across the inner mitochondrial membrane.
    1. Neuroscience

    Retrieval practice facilitates memory updating by enhancing and differentiating medial prefrontal cortex representations

    Zhifang Ye et al.
    Retrieval practice strongly engages the medial prefrontal cortex to integrate and differentiate memory representations, resulting in more effective memory updating.

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