A novel mechanism links two myosins associated with deafness in auditory organs.

A 3D bone marrow niche that reproduces megakaryocyte differentiation and ex vivo platelet production from hematopoietic progenitors and iPSCs of thrombocytopenic patients predicts individual response to Eltrombopag accurately.

Styxl2, a sarcomeric muscle-specific pseudophosphatase in vertebrates, functions in sarcomere assembly by promoting protein degradation of non-muscle myosin IIs.

Global gene expression analysis unravels the underlying mechanisms for distinct crude oil induced defects in Atlantic haddock eggs and larvae.

SSH2, a Slingshot phosphatase required for male fertility, participates in acrosome biogenesis via the control of actin remodeling during spermatid development.

Mutation E334Q in cytoskeletal γ-actin leads to impaired interaction of actin filaments with actin-binding proteins belonging to the myosin and ADF/cofilin families.

Individual nonmuscle myosin 2 filaments in cells may differ their mechanical and kinetic properties depending on the myosin paralog composition giving the cells a mechanism for fine tuning the output of a given nonmuscle myosin filament.

T cell receptor signaling is regulated by newly polymerized F-actin foci at the immunological synapse.