36 results found
    1. Evolutionary Biology
    2. Genetics and Genomics
    Medaka illustration

    The Natural History of Model Organisms: The untapped potential of medaka and its wild relatives

    Leon Hilgers, Julia Schwarzer
    Studies of medaka and other ricefishes in the wild could provide insights in fields such as evolutionary biology, development and cancer research.
    1. Ecology
    2. Neuroscience

    Individual recognition and the ‘face inversion effect’ in medaka fish (Oryzias latipes)

    Mu-Yun Wang, Hideaki Takeuchi
    Medaka fish were able to use faces for individual recognition, and were slower to recognise inverted faces but not inverted non-face shapes.
    1. Stem Cells and Regenerative Medicine

    Activating the regenerative potential of Müller glia cells in a regeneration-deficient retina

    Katharina Lust, Joachim Wittbrodt
    Müller glia cells in the medaka (Oryzias latipes) retina act as lineage restricted progenitors which only regenerate photoreceptors but can be activated to perform as potent stem cells using Sox2.
    1. Computational and Systems Biology
    2. Developmental Biology

    Retinal stem cells modulate proliferative parameters to coordinate post-embryonic morphogenesis in the eye of fish

    Erika Tsingos, Burkhard Höckendorf ... Joachim Wittbrodt
    3D niche topology imposes a spatially biased random stem cell loss, which is differentially fine-tuned in neural retina and retinal pigmented epithelium to regulate growth, shape, and cellular topology.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Cystic proliferation of germline stem cells is necessary to reproductive success and normal mating behavior in medaka

    Luisa F Arias Padilla, Diana C Castañeda-Cortés ... Juan I Fernandino
    In medaka fish, the reduction of cystic proliferation of germ stem cells declines gametogenesis, reproduction success, and male sexual behavior, with a decrease of mating vigor.
    1. Developmental Biology

    Reciprocal analyses in zebrafish and medaka reveal that harnessing the immune response promotes cardiac regeneration

    Shih-Lei Lai, Rubén Marín-Juez ... Didier YR Stainier
    Timely macrophage recruitment is essential for neovascularization and neutrophil clearance during cardiac regeneration.
    1. Developmental Biology
    2. Genetics and Genomics

    Precise in vivo functional analysis of DNA variants with base editing using ACEofBASEs target prediction

    Alex Cornean, Jakob Gierten ... Joachim Wittbrodt
    An integrated framework for in vivo base edting allows to scalably validate candidate genes and DNA variants.
    1. Developmental Biology

    Endogenous protein tagging in medaka using a simplified CRISPR/Cas9 knock-in approach

    Ali Seleit, Alexander Aulehla, Alexandre Paix
    Highly efficient, precise, and scalable CRISPR/Cas9-mediated generation of endogenously tagged alleles in a vertebrate model.
    1. Developmental Biology
    2. Genetics and Genomics

    Efficient single-copy HDR by 5’ modified long dsDNA donors

    Jose Arturo Gutierrez-Triana, Tinatini Tavhelidse ... Joachim Wittbrodt
    The 5' modification of the donor template facilitates highly efficient Crispr targeted homologous recombination and at the same time favors single copy integration.
    1. Neuroscience

    Male-predominant galanin mediates androgen-dependent aggressive chases in medaka

    Junpei Yamashita, Akio Takeuchi ... Kataaki Okubo
    In medaka fish, galanin-expressing neurons in the medial preoptic area occur nearly exclusively in males and mediate androgen-dependent male–male aggressive chases.

Refine your results by:

Type
Research categories