Organ-selective drug action of traditional Chinese medicine that generates systemic immune mediators is proposed and reviewed as a novel mechanistic angle to develop new immunomodulatory drugs.
Kira Delmore, Juan Carlos Illera ... Miriam Liedvogel
Variation in migration can evolve rapidly and traits that comprise this behaviour may be determined by standing variation at a few regulatory regions that are not common across taxonomic groups.
Sven Schenk, Stephanie C Bannister ... Kristin Tessmar-Raible
A molecular profiling approach to quantify transcripts and proteins from identical samples allows study of molecular effects of maturation, sexual differentiation and the endogenous circalunar clock in a marine worm.
Advanced statistical and computational methods are reviewed and compared for integrating microbiome, host genomics, and metabolomics data, together with future research directions.
Jacob L Johansen, Lauren E Nadler ... Jodie Rummer
The ability of animals to adjust to thermal stress is critical for survival under global warming, yet the adjustment process and scope have (until now) remained obscure in marine fishes.
Elimination of extreme reporters using Goldberg cutoffs does not always produce unbiased estimates of associations between nutrition intakes and health outcomes.
The likelihood to perform tool use during foraging is linked to personality traits in ants, suggesting an original interplay between consistent inter-individual variability and division of labor in social species.
Evolutionary changes in cuticular hydrocarbons, a lipid layer on the insect epicuticle, underlie the evolution of desiccation resistance in Drosophila species.