46 results found
    1. Microbiology and Infectious Disease

    Distinct cytoskeletal proteins define zones of enhanced cell wall synthesis in Helicobacter pylori

    Jennifer A Taylor et al.
    The helical bacterium Helicobacter pylori patterns cell wall synthesis using two distinct cytoskeletal proteins, CcmA and MreB, to achieve its characteristic shape.
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    Crenactin forms actin-like double helical filaments regulated by arcadin-2

    Thierry Izoré et al.
    Close evolutionary relationship between eukaryotic F-actin and crenarchaeal crenactin protein is supported by a near-atomic cryoEM structure of double helical filaments, that are inhibited by arcadin-2 through binding to crenactin's hydrophobic groove.
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    The transpeptidase PBP2 governs initial localization and activity of the major cell-wall synthesis machinery in E. coli

    Gizem Özbaykal et al.
    For initiation of cell-wall insertion, the cross-linking enzyme PBP2 stably binds to a component of the cell envelope that is different from MreB filaments.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Bacterial actin MreB forms antiparallel double filaments

    Fusinita van den Ent et al.
    The prokaryotic actin homologue MreB forms antiparallel double filaments in vitro and in vivo, an architecture that is unprecedented among the actin family of proteins.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Flotillin-mediated membrane fluidity controls peptidoglycan synthesis and MreB movement

    Aleksandra Zielińska et al.
    Correct cell wall synthesis in bacteria depends on flotillin-mediated membrane fluidity.
    1. Microbiology and Infectious Disease

    Plasticity of Escherichia coli cell wall metabolism promotes fitness and antibiotic resistance across environmental conditions

    Elizabeth A Mueller et al.
    Environmental specialization of bacterial cell wall synthases influences intrinsic resistance to cell wall active antibiotics.
    1. Neuroscience

    Reinstatement of long-term memory following erasure of its behavioral and synaptic expression in Aplysia

    Shanping Chen et al.
    Storage of long-term memory in Aplysia does not require stable synapses.
    1. Developmental Biology

    MicroRNA-934 is a novel primate-specific small non-coding RNA with neurogenic function during early development

    Kanella Prodromidou et al.
    Primate-specific miR-934 mediates neurogenesis and downstream neuronal differentiation processes, modulating the expression of genes associated with the subplate, a region most prominent in primates, emerging during early cortical development.
    1. Biochemistry and Chemical Biology

    Membrane-partitioned cell wall synthesis in mycobacteria

    Alam García-Heredia et al.
    Mycobacteria employ plasma membrane compartments to organize their cell wall synthesis, and the finalized cell wall compartmentalizes the plasma membrane to promote an environment conducive to its own synthesis.
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    Cytoskeleton: The mother of all actins?

    Felipe Merino, Stefan Raunser
    Insight
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