146 results found
  1. The silhouette of a head over a watercolour background

    Episode 62: December 2019

    In this episode we hear about bomb-proof tardigrades, how tuberculosis gets transmitted between cows and badgers, why ants do not get stuck in traffic jams, the state of mental health in academia and more.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease
    Tropical disease

    Tropical Disease: A Collection of Articles

    Edited by Prabhat Jha et al.
    eLife has published papers on many tropical diseases, including malaria, Ebola, leishmaniases, Dengue and African sleeping sickness.
  2. May 2015

    Episode 20: May 2015

    In this episode we hear about echolocation, bacteriophages, babies and pain, a neural code for food abundance, and how zebrafish can make their own sunscreen.
  3. February 2015

    Episode 18: February 2015

    In this episode we hear about TB, HIV, social behaviour in ants, genetics in baboons and a surprising twist to the handshake.
  4. Episode 39: Spotlight on tropical diseases

    In this special episode we discuss diseases that are common in tropical countries including tuberculosis, Zika, malaria and schistosomiasis.
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Inter-species population dynamics enhance microbial horizontal gene transfer and spread of antibiotic resistance

    Robert M Cooper et al.
    Killing their neighbors allows bacteria to steal genes, including antibiotic resistance genes, which we observed under a microscope, quantified, modeled, and predicted potentially guiding strategies to combat it.
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    Single-protein detection in crowded molecular environments in cryo-EM images

    J Peter Rickgauer et al.
    High-resolution template matching makes small, densely embedded proteins detectable.
    1. Evolutionary Biology

    Robust and accurate prediction of residue–residue interactions across protein interfaces using evolutionary information

    Sergey Ovchinnikov et al.
    Co-evolving residue pairs in the different components of a protein complex almost always make contact across the protein–protein interface, thus providing powerful restraints for the modeling of protein complexes.
    1. Human Biology and Medicine
    2. Immunology and Inflammation

    Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis

    Jose U Scher et al.
    The sequencing of microbial genomes reveals that the presence of a particular microbial species in the gut may increase the risk of the autoimmune disease rheumatoid arthritis.
    1. Microbiology and Infectious Disease

    Factors essential for L,D-transpeptidase-mediated peptidoglycan cross-linking and β-lactam resistance in Escherichia coli

    Jean-Emmanuel Hugonnet et al.
    Production of the L,D-transpeptidase YcbB and elevated synthesis of the (p)ppGpp alarmone reveals a new mode of peptidoglycan polymerization that bypasses the D,D-transpeptidase activity of PBPs and leads to broad-spectrum β-lactam resistance in Escherichia coli.

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