Secretion and fibrillogenesis of collagen-I are separately controlled molecular pathways in the fibroblast, where surprisingly endocytic recycling is required for fibril formation and is increased in fibrotic fibroblasts.
Nicolas Flaugnatti, Loriane Bader ... Melanie Blokesch
Capsular polysaccharides of Acinetobacter baumannii regulate type VI secretion system activity, balancing self-protection with interbacterial competitiveness.
High-throughput animal tracking and quantitative behaviour analysis detects diverse phenotypes in genetic disease models at a scale that makes drug screens possible.
Single-molecule localization imaging shows that the Nipah virus fusion protein forms nanoscale clusters on cell and viral membranes that favor membrane fusion activation.