Solid state NMR is unable to detect any association of substrate to the second binding site, S2, in the extracellular vestibule of the Neurotransmitter:Sodium Symporter LeuT.

Height in early adulthood is an indicator that integrates across different dimensions of sustainable human development with links to health and longevity, nutrition, education and economic productivity.

Molecular simulations, small-angle X-ray and neutron scattering experiments and previously measured NMR experiments were combined to study the structure and dynamics of the proteins and lipids in a nanodisc.

Ketamine, an NMDA receptor antagonist and experimental model for schizophrenia, produces decision-making deficits in monkeys, which are predicted by a lowering of cortical excitation-inhibition balance in a spiking circuit model.

The nonsense-mediated RNA decay (NMD) branch-specific factor UPF3B influences olfactory sensory neuron cell populations, the olfactory receptor repertoire, and antimicrobial gene expression.

Mechanistic insight into the chaperone-like activity of NMNAT to phosphorylated Tau reveals a connection between NAD⁺metabolism and Tau homeostasis.

The small molecule NMDA-receptor antagonist MK801 has been genetically targeted to specific cell types in brain tissue to examine the role of NMDA receptors in cocaine-induced synaptic plasticity.

Molecular engineering can generate light-sensitive NMDA receptors with specific subunit combinations.

Genetic and biochemical analyses demonstrate that cell-surface lectin receptors can potentially function as extracellular NAD⁺-binding receptors and provide direct evidence for extracellular NAD⁺ being a bona fide endogenous signaling molecule in plants.

NMR-based flux measurements show that both bacterial and human Hsp70 chaperones interact with helical, as well as sheet substrates predominantly through a conformational selection mechanism.