3,540 results found
    1. Epidemiology and Global Health

    Urinary metabolic biomarkers of diet quality in European children are associated with metabolic health

    Nikos Stratakis, Alexandros P Siskos ... Leda Chatzi
    Urinary metabolic signatures relate to adherence to the Mediterranean diet and ultra-processed food intake in childhood and reflect associations of these diet quality indicators with metabolic health.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Zika virus remodels and hijacks IGF2BP2 ribonucleoprotein complex to promote viral replication organelle biogenesis

    Clément Mazeaud, Stefan Pfister ... Laurent Chatel-Chaix
    Through interactions with viral RNA and NS5, Zika virus changes the composition of the IGF2BP2-containing ribonucleoprotein complex for the benefit of the viral RNA amplification step of its life cycle.
    1. Genetics and Genomics

    Multi-ancestry meta-analysis of host genetic susceptibility to tuberculosis identifies shared genetic architecture

    Haiko Schurz, Vivek Naranbhai ... International Tuberculosis Host Genetics Consortium
    Results from the largest tuberculosis genome-wide association study meta-analysis identified a significant association in the human leukocyte antigen class II region, rs28383206, across multiple populations.
    1. Genetics and Genomics

    The genetic risk of gestational diabetes in South Asian women

    Amel Lamri, Jayneel Limbachia ... Sonia S Anand
    A type 2 diabetes polygenic risk score and family history of diabetes are strongly and independently associated with multiple gestational diabetes-related traits in women of South Asian descent.
    1. Genetics and Genomics

    Genetic and environmental influences on adult human height across birth cohorts from 1886 to 1994

    Aline Jelenkovic, Yoon-Mi Hur ... Karri Silventoinen
    Genetic variance of adult human height shows a generally increasing trend across the birth-year cohorts but heritability estimates do not present any clear pattern of secular changes over a century.
    1. Neuroscience

    Internal amino acid state modulates yeast taste neurons to support protein homeostasis in Drosophila

    Kathrin Steck, Samuel J Walker ... Carlos Ribeiro
    Two different classes of taste receptor neurons in the Drosophila melanogaster proboscis play distinct roles in yeast feeding and are both modulated by the fly's internal amino acid state in order to promote protein-specific appetite.
    1. Physics of Living Systems

    Arnold tongue entrainment reveals dynamical principles of the embryonic segmentation clock

    Paul Gerald Layague Sanchez, Victoria Mochulska ... Alexander Aulehla
    A microfluidic experimental approach combined with dynamical systems theory reveals how to entrain an embryonic oscillator, the segmentation clock, and allows for the quantification of its entrainment properties.
    1. Developmental Biology
    2. Immunology and Inflammation

    A single-cell survey of Drosophila blood

    Sudhir Gopal Tattikota, Bumsik Cho ... Norbert Perrimon
    Single-cell RNA sequencing of Drosophila hemocytes in blood distinguishes various states within known blood cell types and implicates a novel role for fibroblast growth factor receptor signaling in inter-hemocyte crosstalk.
    1. Ecology

    Mummified baboons reveal the far reach of early Egyptian mariners

    Nathaniel J Dominy, Salima Ikram ... Paul L Koch
    The fabled land of Punt is mapped for the first time using quantitative methods from the disciplines of primatology, geochemistry, and geography.
    1. Microbiology and Infectious Disease

    Functional insights from a surface antigen mRNA-bound proteome

    Larissa Melo do Nascimento, Franziska Egler ... Esteban Erben
    A robust procedure to purify mRNAs and their associated proteins identify CFB2 as the critical protein that binds and influences the fate of the main virulence factor in Trypanosoma brucei.

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