79 results found
    1. Cell Biology

    Ezrin defines TSC complex activation at endosomal compartments through EGFR-AKT signaling

    Giuliana Giamundo, Daniela Intartaglia ... Ivan Conte
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Convincing
    1. Structural Biology and Molecular Biophysics

    Engineering cardiolipin binding to an artificial membrane protein reveals determinants for lipid-mediated stabilization

    Mia L Abramsson, Robin A Corey ... Michael Landreh
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Cell Biology

    Calcium tunneling through the ER and transfer to other organelles for optimal signaling in Toxoplasma gondii

    Zhu-Hong Li, Beejan Asady ... Silvia NJ Moreno
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Structural Biology and Molecular Biophysics

    Atomic-Level Free Energy Landscape Reveals Cooperative Symport Mechanism of Melibiose Transporter

    Ruibin Liang, Lan Guan
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    • Incomplete
    1. Neuroscience

    Circadian regulation of endoplasmic reticulum calcium response in cultured mouse astrocytes

    Ji Eun Ryu, Kyu-Won Shim ... Eun Young Kim
    Astrocytic ER calcium release and gap junction communication exhibit circadian modulation driven by HERPUD1, highlighting the importance of astrocytic circadian rhythms in brain function.
    1. Cell Biology
    2. Plant Biology

    Autophagosome development and chloroplast segmentation occur synchronously for piecemeal degradation of chloroplasts

    Masanori Izumi, Sakuya Nakamura ... Shinya Hagihara
    A plant autophagy pathway transports chloroplast stroma and envelope components into the vacuole through the division and encapsulation of the site of chloroplasts that is associated with developing autophagosome.
    1. Neuroscience

    Cestode larvae excite host neuronal circuits via glutamatergic signaling

    Anja de Lange, Hayley Tomes ... Joseph V Raimondo
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Convincing
    1. Cell Biology
    2. Physics of Living Systems

    Neutrophils actively swell to potentiate rapid migration

    Tamas L Nagy, Evelyn Strickland, Orion D Weiner
    Actin-independent water influx complements actin-driven cytoskeletal forces to potentiate chemoattractant-induced migration in primary human neutrophils.
    1. Biochemistry and Chemical Biology

    A multi-hierarchical approach reveals d-serine as a hidden substrate of sodium-coupled monocarboxylate transporters

    Pattama Wiriyasermkul, Satomi Moriyama ... Shushi Nagamori
    An unbiased approach unveils a non-canonical substrate of the known transporters, highlighting the mechanism behind the use of D-serine as a kidney biomarker.
    1. Structural Biology and Molecular Biophysics

    Mobile barrier mechanisms for Na+-coupled symport in an MFS sugar transporter

    Parameswaran Hariharan, Yuqi Shi ... Lan Guan
    The use of a conformation-selective inhibitory nanobody provides critical information on MelB at a low-sugar affinity inward-facing Na+-bound state for establishing the mobile barrier and substrate-releasing mechanisms.

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