1,341 results found
    1. Plant Biology

    A virus responds instantly to the presence of the vector on the host and forms transmission morphs

    Alexandre Martinière, Aurélie Bak ... Martin Drucker
    Cauliflower mosaic virus reacts immediately when aphids feed on the host plant, and this boosts its chances of being taken up and transmitted by the insects to a new plant.
    1. Microbiology and Infectious Disease

    Strong inter-population cooperation leads to partner intermixing in microbial communities

    Babak Momeni, Kristen A Brileya ... Wenying Shou
    Simulations and experiments on systems containing two different populations of microorganisms show that interactions that benefit at least one of the populations can lead to communities with stable compositions, and that strong cooperation between two populations can lead to communities in which both populations are mixed together.
    1. Structural Biology and Molecular Biophysics
    2. Microbiology and Infectious Disease

    Influenza-virus membrane fusion by cooperative fold-back of stochastically induced hemagglutinin intermediates

    Tijana Ivanovic, Jason L Choi ... Stephen C Harrison
    Long-lived intermediate states formed by glycoprotein catalysts are an essential part of the process used by influenza virus particles to infect cells.
    1. Structural Biology and Molecular Biophysics
    2. Neuroscience

    Structure of a pore-blocking toxin in complex with a eukaryotic voltage-dependent K+ channel

    Anirban Banerjee, Alice Lee ... Roderick MacKinnon
    Charybdotoxin, a toxin produced by scorpions, blocks a K+ channel by binding in a lock-and-key fashion to the mouth of the channel and presenting a lysine amino group, which serves as a K+ mimic in the selectivity filter.
    1. Cell Biology

    TRPM5-mediated calcium uptake regulates mucin secretion from human colon goblet cells

    Sandra Mitrovic, Cristina Nogueira ... Vivek Malhotra
    Goblet cells secrete mucins—which are key components of mucus—in a process that is regulated by calcium ions, which enter the goblet cells via a mechanism involving a channel protein called TRPM5.
    1. Physics of Living Systems

    Sequence-dependent base pair stepping dynamics in XPD helicase unwinding

    Zhi Qi, Robert A Pugh ... Yann R Chemla
    The ability of an enzyme called XPD helicase to unwind the double helix is influenced by the DNA sequence and the availability of energy.
    1. Chromosomes and Gene Expression

    The homologous recombination machinery modulates the formation of RNA–DNA hybrids and associated chromosome instability

    Lamia Wahba, Steven K Gore, Douglas Koshland
    When a protein involved in DNA repair malfunctions, it can anneal RNA molecules to DNA molecules, creating hybrids that increase the frequency of mutations in the DNA.
    1. Plant Biology

    Arabidopsis plants perform arithmetic division to prevent starvation at night

    Antonio Scialdone, Sam T Mugford ... Martin Howard
    Plants implement arithmetic division to optimize use of carbohydrate reserves and thus maintain metabolism and growth at night.
    1. Structural Biology and Molecular Biophysics

    Direct single molecule measurement of TCR triggering by agonist pMHC in living primary T cells

    Geoff P O'Donoghue, Rafal M Pielak ... Jay T Groves
    Quantitative observations of single-molecule binding between antigen and T cell receptor (TCR) in living primary T cells reveals unbinding kinetics, stoichiometry and signaling molecule recruitment, providing insights into the mechanisms of antigen recognition by the immune system.
    1. Structural Biology and Molecular Biophysics
    2. Microbiology and Infectious Disease

    In situ structural analysis of the Yersinia enterocolitica injectisome

    Mikhail Kudryashev, Marco Stenta ... Henning Stahlberg
    The basal body of the type-III secretion system of Yersinia enterocolitica within bacterial membranes shows elasticity and is longer than related isolated systems.

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