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    1. Chromosomes and Gene Expression

    Decapping activators Edc3 and Scd6 act redundantly with Dhh1 in post-transcriptional repression of starvation-induced pathways

    Rakesh Kumar, Fan Zhang ... Alan G Hinnebusch
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    1. Neuroscience

    The identification of extensive samples of motor units in human muscles reveals diverse effects of neuromodulatory inputs on the rate coding

    Simon Avrillon, François Hug ... Dario Farina
    Motor units within a pool exhibit distinct rate coding as force levels change, highlighting how gain control can transform inputs with limited bandwidth into the desired muscle force.
    1. Structural Biology and Molecular Biophysics

    RNA tertiary structure and conformational dynamics revealed by BASH MaP

    Maxim Oleynikov, Samie R Jaffrey
    BASH MaP quantitatively reveals alternative RNA tertiary structures by enabling dimethyl sulfate to probe the presence of nucleobase interactions on the Watson-Crick and Hoogsteen faces of single RNA molecules.
    1. Neuroscience

    Sequential replacement of PSD95 subunits in postsynaptic supercomplexes is slowest in the cortex

    Katie Morris, Edita Bulovaite ... Mathew H Horrocks
    PSD95 supercomplexes maintain long-term stability through gradual subunit replacement, with the slowest turnover in cortical synapses associated with memory storage.
    1. Microbiology and Infectious Disease

    Bacillus velezensis HBXN2020 alleviates Salmonella Typhimurium infection in mice by improving intestinal barrier integrity and reducing inflammation

    Linkang Wang, Haiyan Wang ... Ping Qian
    Bacillus velezensis has broad-spectrum antibacterial activity and can reduce the colonization of Salmonella Typhimurium in the intestinal tract of mice.
    1. Immunology and Inflammation

    Diversity and functional specialization of oyster immune cells uncovered by integrative single cell level investigations

    Sébastien de La Forest Divonne, Juliette Pouzadoux ... Emmanuel Vignal
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    Sequence action representations contextualize during rapid skill learning

    Debadatta Dash, Fumiaki Iwane ... Leonardo G Cohen
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Genetics and Genomics

    An ancient competition for the conserved branchpoint sequence influences physiological and evolutionary outcomes in splicing

    Karen Larissa Pereira de Castro, Jose M Abril ... W Samuel Fagg
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Genetics and Genomics

    Perturbations in eIF3 subunit stoichiometry alter expression of ribosomal proteins and key components of the MAPK signaling pathways

    Anna Herrmannová, Jan Jelínek ... Leoš Shivaya Valášek
    eIF3, despite being a general translation initiation factor, functions in mRNA-specific regulation, having a profound impact on the synthesis and activation of the MAPK pathway components and ribosomal proteins.
    1. Structural Biology and Molecular Biophysics

    Elucidating ATP’s role as solubilizer of biomolecular aggregate

    Susmita Sarkar, Saurabh Gupta ... Jagannath Mondal
    ATP prevents condensation of aggregation-prone intrinsically disordered protein by modulating its conformation.
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