Voice your concerns about research culture and research communication: Have your say in our 7th annual survey.
41 results found
    1. Developmental Biology
    2. Evolutionary Biology

    Germ layer-specific regulation of cell polarity and adhesion gives insight into the evolution of mesoderm

    Miguel Salinas-Saavedra et al.
    The expression of 'bilaterian-mesodermal’ genes changes the epithelial properties of the endomesoderm during the embryogenesis of the cnidarian Nematostella vectensis.
    1. Developmental Biology
    2. Evolutionary Biology

    Hedgehog signaling is required for endomesodermal patterning and germ cell development in the sea anemone Nematostella vectensis

    Cheng-Yi Chen et al.
    The dependence of Nematostella germ cell specification on zygotic Hedgehog pathway activity supports the hypothesis that the eumetazoan common ancestor segregated its germline by inductive signals rather than maternal determinants.
    1. Ecology
    2. Evolutionary Biology

    Dynamics of venom composition across a complex life cycle

    Yaara Y Columbus-Shenkar et al.
    Different developmental stages of a venomous animal (e.g. Nematostella vectensis) with a complex life cycle produce vastly different venoms that can serve in different antagonistic interactions with other species.
    1. Neuroscience
    2. Structural Biology and Molecular Biophysics

    A molecular filter for the cnidarian stinging response

    Keiko Weir et al.
    Cnidarian stinging cells use a specialized voltage-gated calcium channel to integrate distinct sensory signals and selectively trigger a predatory response.
    1. Developmental Biology
    2. Evolutionary Biology

    CRISPR knockouts reveal an endogenous role for ancient neuropeptides in regulating developmental timing in a sea anemone

    Nagayasu Nakanishi, Mark Q Martindale
    Analysis of the endogenous function of deeply conserved neuropeptides in sea anemones sheds light on a primitive role of nervous systems in modulating developmental timing.
    1. Structural Biology and Molecular Biophysics

    Structure of a TRPM2 channel in complex with Ca2+ explains unique gating regulation

    Zhe Zhang et al.
    The 3Å structure and correlated functional analysis of the TRPM2 cation channel from Nematostella vectensis shed light on the molecular mechanisms of TRPM2 regulation by intra- and extracellular Ca2+, and of inactivation of human TRPM2.
    1. Developmental Biology
    2. Evolutionary Biology

    Landscape of histone modifications in a sponge reveals the origin of animal cis-regulatory complexity

    Federico Gaiti et al.
    The complex chromatin-based genomic regulatory system controlling developmental gene expression in complex bilaterians predates the evolution of morphological complexity and may have been a prerequisite for the evolution of the first simple multicellular animals.
    1. Developmental Biology
    2. Evolutionary Biology

    Par protein localization during the early development of Mnemiopsis leidyi suggests different modes of epithelial organization in the metazoa

    Miguel Salinas-Saavedra, Mark Q Martindale
    Even though the ctenophore Mnemiopsis leidyi develops polarized epithelial tissues, polarization is not mediated by the conserved mechanisms polarizing bilaterian and cnidarian epithelial cells.
    1. Structural Biology and Molecular Biophysics

    Global alignment and assessment of TRP channel transmembrane domain structures to explore functional mechanisms

    Katherine E Huffer et al.
    Structure-based alignment of TRP channels enables comparison of structural changes, ion permeation pathways and ligand-binding sites and reveals over-representation of structures that represent non-conducting states.

Refine your results by:

Type
Research categories