Site-specific modification of NEMO facilitates RANKL signal specificity in myeloid progenitors and serves as a potential target to modulate inflammatory osteolysis through ISG15-dependent autophagy.

Auxiliary subunits Neto1 and Neto2 regulate the GluK1 receptor targeting to excitatory silent synapses through different molecular mechanisms and also modify receptor biophysics through distinct mechanisms.

Insecticide-treated net requirements for Africa have been underestimated, but mitigating for inefficiencies in net distributions can produce a cost effective path to universal coverage.

A computer model built on insights gained from comprehensive experimental analysis reveals mechanisms of blood stem cell regulation.

Accumulation of perineuronal nets around parvalbumin (PV)-positive inhibitory interneurons closes visual cortical plasticity by selectively down-regulating thalamic synapses onto PV cells in a sensory-dependent manner.

Nemo-like kinase is a key protein promoting the pathogenesis of spinal and bulbar muscular atrophy.

The Mtgr1 protein promotes the maintenance of pluripotency and germ cell formation via its interaction with the stem cell regulator Prdm14.

To protect mammals against retroviral infections, TRIM5 restriction factors recognize viral capsids by forming complementary hexagonal nets that can adapt to the patterns of capsid protein subunits on the viral capsid surface.

NETs induction, a central component of the innate immune response, utilises assorted signalling pathways as demonstrated through the analysis of healthy and patient neutrophils treated with five distinct stimuli.

A multiscale computational nerve net model describes how the activity of individual neurons controls the swimming motion of a jellyfish in its hydrodynamic environment.