160 results found
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Functional genomics of lipid metabolism in the oleaginous yeast Rhodosporidium toruloides

    Samuel T Coradetti, Dominic Pinel ... Jeffrey M Skerker
    Using barcoded mutagenesis and a high-throughput genetic screen results in the identification of 150 genes that affect lipid accumulation in a non-model yeast system.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Analysis of CDPK1 targets identifies a trafficking adaptor complex that regulates microneme exocytosis in Toxoplasma

    Alex W Chan, Malgorzata Broncel ... Sebastian Lourido
    Comprehensive characterization of kinase-dependent phosphorylation in the human pathogen Toxoplasma gondii identifies a trafficking adaptor complex required for virulence factor secretion and infection.
    1. Genetics and Genomics
    2. Neuroscience

    Steady-state neuron-predominant LINE-1 encoded ORF1p protein and LINE-1 RNA increase with aging in the mouse and human brain

    Tom Bonnifet, Sandra Sinnassamy ... Julia Fuchs
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Microbiology and Infectious Disease

    Defining the function of OmpA in the Rcs stress response

    Kilian Dekoninck, Juliette Létoquart ... Jean-Francois Collet
    In vivo and in vitro approaches uncover a new function for the β-barrel OmpA and reveal how it interacts with the stress sensor lipoprotein RcsF.
    1. Genetics and Genomics

    SERBP1 interacts with PARP1 and is present in PARylation-dependent protein complexes regulating splicing, cell division, and ribosome biogenesis

    Kira Breunig, Xiufen Lei ... Luiz OF Penalva
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    • Compelling
    1. Cancer Biology

    Use of signals of positive and negative selection to distinguish cancer genes and passenger genes

    László Bányai, Maria Trexler ... László Patthy
    In contrast with earlier conclusions, negative selection has a major role in cancer evolution.
    1. Genetics and Genomics

    Beyond A and B Compartments: how major nuclear locales define nuclear genome organization and function

    Omid Gholamalamdari, Tom van Schaik ... Andrew S Belmont
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Physics of Living Systems

    Diameter dependence of transport through nuclear pore complex mimics studied using optical nanopores

    Nils Klughammer, Anders Barth ... Cees Dekker
    Nuclear pore complex mimics based on solid-state nanopores show significant selectivity below a diameter of 55 nm, which decreases gradually for larger pore diameters.
    1. Developmental Biology
    2. Plant Biology

    Formation of polarity convergences underlying shoot outgrowths

    Katie Abley, Susanna Sauret-Güeto ... Enrico Coen
    Models that generate tandem alignments of cell polarities are more readily compatible with the formation of PIN1 polarity patterns in plant leaf buds than the most widely accepted “up-the-gradient” model.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Export of discarded splicing intermediates requires mRNA export factors and the nuclear basket

    Yi Zeng, Jonathan P. Staley
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing

Refine your results by:

Type
Research categories