55 results found
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Virophages and retrotransposons colonize the genomes of a heterotrophic flagellate

    Thomas Hackl et al.
    Mutualistic viruses called virophages are common genome inhabitants of a marine protist, where they may protect host populations from giant viruses.
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Misic, a general deep learning-based method for the high-throughput cell segmentation of complex bacterial communities

    Swapnesh Panigrahi et al.
    A broadly applicable deep-learning based method that recognizes rod-shaped bacteria of virtually any species in complex bacterial communities.
    1. Genetics and Genomics
    2. Neuroscience

    Translational control of polyamine metabolism by CNBP is required for Drosophila locomotor function

    Sonia Coni et al.
    A decrease of the type 2 myotonic dystrophy gene product CNBP causes an impairment of polyamine metabolism and locomotor dysfunction that can be reverted with polyamine supplementation.
    1. Chromosomes and Gene Expression
    2. Computational and Systems Biology

    How subtle changes in 3D structure can create large changes in transcription

    Jordan Yupeng Xiao et al.
    Promoter futile cycles can explain how subtle differences in genome folding sometimes generate large difference in gene expression.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    BET family members Bdf1/2 modulate global transcription initiation and elongation in Saccharomyces cerevisiae

    Rafal Donczew, Steven Hahn
    Yeast bromodomain-containing factors Bdf1/2 offer insights into the biological role of the BET family of transcriptional regulators, which is a promising target in cancer therapy.
    1. Cell Biology
    2. Developmental Biology

    Single-cell transcriptome analysis defines heterogeneity of the murine pancreatic ductal tree

    Audrey M Hendley et al.
    Single-cell RNA-sequencing analyses and functional studies define heterogeneity within the pancreatic ductal tree and unique properties of subpopulations of duct cells including an epithelial-mesenchymal transcriptomic axis and roles in chronic pancreatic inflammation.
    1. Developmental Biology
    2. Genetics and Genomics

    Cell competition removes segmental aneuploid cells from Drosophila imaginal disc-derived tissues based on ribosomal protein gene dose

    Zhejun Ji et al.
    Cell competition is an important mechanism selecting against aneuploid cells.
    1. Cell Biology

    In vivo reconstitution finds multivalent RNA–RNA interactions as drivers of mesh-like condensates

    Weirui Ma et al.
    Binding of a multivalent RNA-binding protein to mRNAs that are able to form pervasive RNA–RNA interactions induces formation of mesh-like condensates, whereas binding of mostly structured mRNAs induces sphere-like condensates.
    1. Evolutionary Biology
    2. Genetics and Genomics

    High-quality carnivoran genomes from roadkill samples enable comparative species delineation in aardwolf and bat-eared fox

    Rémi Allio et al.
    High-quality genomes can be obtained from roadkill samples and used in population genomics for species delimitation with conservation implications.
    1. Structural Biology and Molecular Biophysics

    Functional implications of MIR domains in protein O-mannosylation

    Antonella Chiapparino et al.
    The MIR domain of protein-O-mannosyltransferases participates in glycosylation by binding mannosylated peptides and regulates enzyme processivity.

Refine your results by:

Type
Research categories