Browse the search results

Page 2 of 6
    1. Chromosomes and Gene Expression
    2. Structural Biology and Molecular Biophysics

    Human LINE-1 retrotransposition requires a metastable coiled coil and a positively charged N-terminus in L1ORF1p

    Elena Khazina, Oliver Weichenrieder
    Human LINE-1 retrotransposition is found to critically depend on the rapidly evolving N-terminal sequence of the LINE-1 ORF1 protein and on the metastability of its coiled coil domain, indicating uncharacterized steps in LINE-1 retrotransposition.
    1. Biochemistry and Chemical Biology
    2. Chromosomes and Gene Expression

    An H3K9 methylation-dependent protein interaction regulates the non-enzymatic functions of a putative histone demethylase

    Gulzhan Raiymbek et al.
    A putative histone demethylase in fission yeast has non-enzymatic properties that regulates heterochromatin assembly and epigenetic inheritance.
    1. Ecology

    The return to water in ancestral Xenopus was accompanied by a novel mechanism for producing and shaping vocal signals

    Ursula Kwong-Brown et al.
    When ancestral Xenopus returned to water ~170mya, they evolved a new method for producing courtship calls underwater without airflow, using vibrations that also preserve essential acoustic information on species identity.
    1. Plant Biology

    Fluctuations of the transcription factor ATML1 generate the pattern of giant cells in the Arabidopsis sepal

    Heather M Meyer et al.
    Fluctuations of a transcription factor that coincide with the G2 phase of the cell cycle pattern two interspersed cell fates in a multicellular system.
    1. Cell Biology
    2. Developmental Biology

    Live imaging of hair bundle polarity acquisition demonstrates a critical timeline for transcription factor Emx2

    Yosuke Tona, Doris K Wu
    Acquisition of hair bundle orientation in sensory hair cells is only sensitive to Emx2 during a critical time window.
    1. Cell Biology

    In vivo reconstitution finds multivalent RNA–RNA interactions as drivers of mesh-like condensates

    Weirui Ma et al.
    Binding of a multivalent RNA-binding protein to mRNAs that are able to form pervasive RNA–RNA interactions induces formation of mesh-like condensates, whereas binding of mostly structured mRNAs induces sphere-like condensates.
    1. Microbiology and Infectious Disease

    Dominant Vibrio cholerae phage exhibits lysis inhibition sensitive to disruption by a defensive phage satellite

    Stephanie G Hays, Kimberley D Seed
    Genetic and molecular analyses identify and characterize an evolutionary battle over lysis timing wherein a bacteriophage delays lysis through lysis inhibition while a defensive phage satellite accelerates lysis.
    1. Evolutionary Biology
    2. Genetics and Genomics

    A de novo evolved gene in the house mouse regulates female pregnancy cycles

    Chen Xie et al.
    A female specifically expressed new protein-coding gene that has emerged out of non-coding sequences without detectable signatures of adaptive evolution affects female pregnancy cycles.
    1. Neuroscience

    Noninvasive quantification of axon radii using diffusion MRI

    Jelle Veraart et al.
    Cell-specific architectural properties such as the axon diameter of the white matter of the human brain can be quantified accurately and non-invasively using diffusion magnetic resonance imaging.
    1. Computational and Systems Biology
    2. Genetics and Genomics

    Hyperosmotic stress memory in Arabidopsis is mediated by distinct epigenetically labile sites in the genome and is restricted in the male germline by DNA glycosylase activity

    Anjar Wibowo et al.
    Transient adaptation to environmental fluctuations in plants is mediated through discrete epigenetic changes.