415 results found
    1. Cell Biology

    Mechanisms of PP2A-Ankle2 dependent nuclear reassembly after mitosis

    Jingjing Li, Xinyue Wang ... Vincent Archambault
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cancer Biology

    The context-dependent epigenetic and organogenesis programs determine 3D vs. 2D cellular fitness of MYC-driven murine liver cancer cells

    Jie Fang, Shivendra Singh ... Jun Yang
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    • Incomplete
    1. Microbiology and Infectious Disease

    Function and firing of the Streptomyces coelicolor contractile injection system requires the membrane protein CisA

    Bastien Casu, Joseph W Sallmen ... Martin Pilhofer
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Plant Biology

    The Rhizobial effector NopT targets Nod factor receptors to regulate symbiosis in Lotus japonicus

    Hanbin Bao, Yanan Wang ... Yangrong Cao
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    The fate of pyruvate dictates cell growth by modulating cellular redox potential

    Ashish G Toshniwal, Geanette Lam ... Jared Rutter
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Cancer Biology

    Unveiling chemotherapy-induced immune landscape remodeling and metabolic reprogramming in lung adenocarcinoma by scRNA-sequencing

    Yiwei Huang, Gujie Wu ... Cheng Zhan
    Chemotherapy remodels lung adenocarcinoma’s tumor microenvironment by driving metabolic reprogramming and shifting immune cell functions to modulate tumor progression and immune responses.
    1. Cell Biology
    2. Neuroscience

    The effects of 17α-estradiol treatment on endocrine system revealed by single-nucleus transcriptomic sequencing of hypothalamus

    Lei Li, Guanghao Wu ... Yinchuan Li
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    A novel human pluripotent stem cell gene activation system identifies IGFBP2 as a mediator in the production of haematopoietic progenitors in vitro

    Paolo Petazzi, Telma Ventura ... Antonella Fidanza
    A novel tool is used to assess gene function in vitro by targeted endogenous transcriptional activation to unveil novel players in development and disease.
    1. Biochemistry and Chemical Biology
    2. Immunology and Inflammation

    SAM transmethylation pathway and adenosine recycling to ATP are essential for systemic regulation and immune response

    Pavla Nedbalova, Nikola Kaislerova ... Tomas Dolezal
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Computational and Systems Biology

    Mitochondrial respiration atlas reveals differential changes in mitochondrial function across sex and age

    Dylan C Sarver, Muzna Saqib ... G William Wong
    Mitochondrial respiration atlas reveals functional signatures of aging across diverse tissues and organ systems.
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