211 results found
    1. Developmental Biology
    2. Genetics and Genomics

    Biallelic variants in MAD2L1BP (p31comet) cause female infertility characterized by oocyte maturation arrest

    Lingli Huang, Wenqing Li ... Jianqiang Bao
    Biallelic MAD2L1BP variants contribute to oocyte metaphase I arrest in women with primary infertility and p31comet is required for human oocyte maturation.
    1. Cell Biology
    2. Evolutionary Biology

    The regulation of oocyte maturation and ovulation in the closest sister group of vertebrates

    Shin Matsubara, Akira Shiraishi ... Honoo Satake
    Oocyte maturation and ovulation in the sister group of vertebrates, Ciona intestinalis Type A, are triggered by Ci-VP, the Ciona homolog of a typical neruopeptide, vasopressin.
    1. Cell Biology

    A genetic screen identifies new steps in oocyte maturation that enhance proteostasis in the immortal germ lineage

    Madhuja Samaddar, Jérôme Goudeau ... Cynthia Kenyon
    A whole-genome genetic screen links new aspects of oocyte maturation to proteostasis renewal in the immortal Caenorhabditis elegans germ-cell lineage and reveals similarities to somatic cell maintenance during aging.
    1. Developmental Biology

    A gonad-expressed opsin mediates light-induced spawning in the jellyfish Clytia

    Gonzalo Quiroga Artigas, Pascal Lapébie ... Evelyn Houliston
    Gamete release in the jellyfish Clytia is mediated by an opsin photopigment expressed in neurosecretory cells of the gonad ectoderm, which release an oocyte maturation hormone in response to light.
    1. Biochemistry and Chemical Biology
    2. Ecology

    Aggregation pheromone 4-vinylanisole promotes the synchrony of sexual maturation in female locusts

    Dafeng Chen, Li Hou ... Xianhui Wang
    4-Vinylanisole acts as maturation-accelerating pheromone to synchronize oocyte maturation of female adults in locusts.
    1. Developmental Biology

    C-type natriuretic peptide improves maternally aged oocytes quality by inhibiting excessive PINK1/Parkin-mediated mitophagy

    Hui Zhang, Chan Li ... Baohua Ma
    In vitro and in vivo data show that C-natriuretic peptide is significant for increasing mitochondrial bioenergetics by cAMP-PKA pathway and improving cytoplasmic and nuclear maturation of maternally aged oocyte.
    1. Cell Biology

    N-cadherin mechanosensing in ovarian follicles controls oocyte maturation and ovulation

    Alaknanda Emery, Orest W. Blaschuk ... Darryl L Russell
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Developmental Biology
    2. Chromosomes and Gene Expression

    mRNA poly(A)-tail changes specified by deadenylation broadly reshape translation in Drosophila oocytes and early embryos

    Stephen W Eichhorn, Alexander O Subtelny ... David P Bartel
    Profiling of mRNA poly(A)-tail lengths and translational efficiencies provides new insights into posttranscriptional gene regulation in early Drosophila development.
    1. Cell Biology

    Progesterone induces meiosis through two obligate co-receptors with PLA2 activity

    Nancy Nader, Lama Assaf ... Khaled Machaca
    Progesterone mediates nongenomic signaling in Xenopus oocyte meiosis by activating a PLA2 activity that requires two membrane receptors ABDH2 and mPRß.
    1. Developmental Biology

    FMNL2 regulates actin for endoplasmic reticulum and mitochondria distribution in oocyte meiosis

    Meng-Hao Pan, Kun-Huan Zhang ... Shao-Chen Sun
    FMNL2 associates with Formin2 and Arp2/3 complex for actin assembly, which further regulates spindle migration and INF2/Cofilin-related organelle dynamics during mammalian oocyte maturation.

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