782 results found
    1. Human Biology and Medicine
    2. Stem Cells and Regenerative Medicine

    Merging organoid and organ-on-a-chip technology to generate complex multi-layer tissue models in a human retina-on-a-chip platform

    Kevin Achberger et al.
    A microphysiological system (retina-on-a-chip) shows the potential to promote drug development and provide new insights into the underlying pathology of retinal diseases.
    1. Cell Biology

    Duodenum Intestine-Chip for preclinical drug assessment in a human relevant model

    Magdalena Kasendra et al.
    Combining Organs-on-Chips technology with adult intestinal organoids provides an improved model of human duodenum and a new platform for preclinical drug assessment.
    1. Human Biology and Medicine
    2. Stem Cells and Regenerative Medicine

    Tissue Engineering: Building a better model of the retina

    Milica Radisic
    Researchers have combined organ-on-a-chip engineering with the benefits of organoids to make improved models of the human retina.
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    1. Human Biology and Medicine

    Human cardiac fibroblasts adaptive responses to controlled combined mechanical strain and oxygen changes in vitro

    Giovanni Stefano Ugolini et al.
    Human cardiac fibroblasts regulate their cellular responses according to the combination of multiple environmental stimuli namely oxygen changes and mechanical signals.
  1. Philosophy of Biology: Health, ecology and the microbiome

    S Andrew Inkpen
    The interactions between communities of microbial species and their human hosts raise questions about the nature of health and disease.
  2. Point of View: Unbridle biomedical research from the laboratory cage

    Garet P Lahvis
    Recent advances in technology now make it possible to carry out biomedical research on animals living in the wild, or captive animals living in naturalistic conditions.
  3. Science Writing Competition: Hip, hip, hooray!

    Emma Pewsey
    The use of X-rays to investigate why bones break could lead to treatments that reduce the number of elderly people who suffer broken hips.
    1. Ecology
    2. Evolutionary Biology

    The Natural History of Model Organisms: New opportunities at the wild frontier

    Jane Alfred, Ian T Baldwin
    A better understanding of the natural history of model organisms will increase their value as model systems and also keep them at the forefront of research.
    1. Human Biology and Medicine
    2. Neuroscience

    Point of View: Predictive regulation and human design

    Peter Sterling
    Why does the human regulatory system, which evolution tuned for small satisfactions, now constantly demand 'more'?
    1. Cell Biology
    2. Computational and Systems Biology

    Science Forum: The Human Cell Atlas

    Aviv Regev et al.
    Advances in techniques for analysing single cells and tissues have inspired an international effort to create comprehensive reference maps of all human cells - the fundamental units of life - as a basis for both understanding human health and diagnosing, monitoring and treating disease.

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