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Impaired voice processing in reward and salience circuits predicts social communication in children with autism
Daniel Arthur Abrams et al.
Children with autism often 'tune out' the voices in their environment and new results show that impaired processing of voices in the brain's reward system may underlie this social behavior.
Computational and Systems Biology
Graphical-model framework for automated annotation of cell identities in dense cellular images
Shivesh Chaudhary et al.
Unbiased and automatic annotation using structured prediction framework with efficiently built data-driven atlases is more accurate than registration-based methods for cell identifications in dense images and enables fast whole-brain analysis.
The Natural History of Model Organisms: Neurogenomic insights into the behavioral and vocal development of the zebra finch
Mark E Hauber et al.
The genetic and behavioral diversity of the zebra finch, both in the wild and in captivity, make it well-suited for neuroethological studies of vocal learning, culture, and social bonding.
Neuronal octopamine signaling regulates mating-induced germline stem cell increase in female
Yuto Yoshinari et al.
Genetic analyses using the fruit fly illustrate how neuronal system couples germline stem cell increase to an external cue, which is mating, through stem cell niche signaling.
Fatty acid β-oxidation is required for the differentiation of larval hematopoietic progenitors in
Satish Kumar Tiwari et al.
Genetic and molecular analyses reveal the decisive role of fatty acid oxidation (FAO) acting downstream to the ROS-JNK circuit essential for hemocyte progenitor differentiation in
Genetics and Genomics
Learning is enhanced by tailoring instruction to individual genetic differences
David G Mets, Michael S Brainard
Tailoring instructive experience to individual genetic biases improves vocal learning outcomes across genetic backgrounds in the Bengalese finch.
Retinal oxygen supply shaped the functional evolution of the vertebrate eye
Christian Damsgaard et al.
Multiple respiratory and vascular mechanisms have recurrently evolved across the vertebrates to alleviate the oxygen diffusion limitations inherent to the morphology of the retina.
In vivo assessment of the neural substrate linked with vocal imitation accuracy
Julie Hamaide et al.
Song learning accuracy can be predicted and traced in the structural properties of the brains of juvenile male zebra finches already at 20 days post-hatching.
Vocal development in a Waddington landscape
Yayoi Teramoto et al.
An integrated landscape framework shows how the coordinated changes in vocal apparatus, muscles, nervous system, and social interaction together influence the trajectory of vocal development.
Immunology and Inflammation
Epigenetic modification of the PD-1 (
) promoter in effector CD4
T cells tolerized by peptide immunotherapy
Rhoanne C McPherson et al.
Peptide immunotherapy in mice depends upon sustained expression of co-inhibitory protein PD-1 in T cells.
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