509 results found
    1. Microbiology and Infectious Disease

    An orphan cbb3-type cytochrome oxidase subunit supports Pseudomonas aeruginosa biofilm growth and virulence

    Jeanyoung Jo et al.
    During growth in biofilms and host infection, the opportunistic pathogen Pseudomonas aeruginosa employs respiratory heterocomplexes that support extracellular electron shuttling and pathogenicity.
    1. Cell Biology
    2. Neuroscience

    Speed and segmentation control mechanisms characterized in rhythmically-active circuits created from spinal neurons produced from genetically-tagged embryonic stem cells

    Matthew J Sternfeld et al.
    Stem cell derived ventral-spinal cord excitatory neurons self-assemble into a rhythmically bursting neural network whose speed and intercellular coordination are both instructively modulated by cell-type specific interactions with inhibitory neurons.
    1. Cell Biology
    2. Developmental Biology

    Genetic screen in Drosophila muscle identifies autophagy-mediated T-tubule remodeling and a Rab2 role in autophagy

    Naonobu Fujita et al.
    Analyses of a developmentally regulated Drosophila myofiber remodeling program provide insight into induced autophagy required for T-tubule membrane reorganization, and uncover a conserved Rab2 role in autophagosome-lysosome fusion.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Extensive cargo identification reveals distinct biological roles of the 12 importin pathways

    Makoto Kimura et al.
    Transport-based high-throughput identification of cargo proteins specific to all 12 human importin-β family nuclear import receptors revealed biological processes that the cargo cohorts of each receptor are involved in.
    1. Genetics and Genomics
    2. Human Biology and Medicine

    Identification of an emphysema-associated genetic variant near TGFB2 with regulatory effects in lung fibroblasts

    Margaret M Parker et al.
    A functional genetic variant, rs1690789, affects susceptibility to emphysema by altering TGFB2 expression in human lung fibroblasts.
    1. Developmental Biology
    2. Plant Biology

    Cell type boundaries organize plant development

    Monica Pia Caggiano et al.
    Leaf position, shape and orientation are pre-patterned by cell type boundaries in the shoot meristem.
    1. Cell Biology
    2. Computational and Systems Biology

    DASC, a sensitive classifier for measuring discrete early stages in clathrin-mediated endocytosis

    Xinxin Wang et al.
    A new user-intervention-free classification, using single-fluorescent markers, measures conventionally unmeasureable phenotypes in early stages during clathrin-mediated endocytosis.
    1. Neuroscience

    Layer 2/3 pyramidal cells in the medial prefrontal cortex moderate stress induced depressive behaviors

    Prerana Shrestha et al.
    The well-established link between stress and depression could be due to the activity of a population of cells in prefrontal cortex that express a gene mutated in the rare disorder Wolfram syndrome.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    MAF1 represses CDKN1A through a Pol III-dependent mechanism

    Yu-Ling Lee et al.
    Pol II-mediated transcription and chromatin looping of CDKN1A are repressed by MAF1 through the regulation of Pol III activity.
    1. Microbiology and Infectious Disease

    A divergent cyclin/cyclin-dependent kinase complex controls the atypical replication of a malaria parasite during gametogony and transmission

    Aurélia C Balestra et al.
    Multiple steps of the atypical cell cycles underlying Plasmodium gametogony are controlled by a divergent cyclin/cyclin-dependent complex.

Refine your results by:

Type
Research categories