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Live-imaging of a transgenic reporter of vascular Erk signalling in zebrafish reveals sequential signalling mechanisms during the initiation of regeneration in wounded blood vessels.

Functional reconstitution of a mammalian P2X7 receptor uncovers an intrinsic and lipid-dependent dye-permeable membrane pore.

Structural and functional analysis of axonal-axonal reciprocal connections between dopamine neurons and Kenyon cells provides insight into the brain computations for normal associative olfactory learning.

A new strategy of memory consolidation disruption based on astrocyte and purinergic signaling, which leads to persistent fear memory attenuation accompanied by reduced fear-related anxiety behavior.

Supporting cells in the cochlea change their shape in response to purinergic receptor activation, which influences hair cell excitability by altering potassium redistribution in the extracellular space.

Biochemical and cellular analyses reveal the mechanism by which EROS regulates NOX2 and P2X7 abundance in mouse and human.

The feedback inhibition of T-type calcium channels by intracellular calcium provides new avenues to better decipher the roles of these low-voltage-activated channels in the fine control of calcium signaling events in physiology and pathophysiology.

The neuropeptide Drosulfakinin (DSK) functions in a subset of DSK neurons to interact with neural nodes in the sex circuit and acts through its receptor CCKLR-17D3 to control female sexual behavior.

Bacteria release ATP as part of their attack in sepsis.

The amino terminus of acid-sensing ion channel 1a forms a reentrant 'loop' that frames the lower pore and harbors a conserved 'His-Gly' motif implicated in gating and ion selectivity mechanisms.