Identification of central neural circuits and sensory pathways underlying social-sexual modulation of sperm ejection in female Drosophila unraveled cryptic mate choice, a mechanism of post-copulatory sexual selection.
A set of sexually dimorphic neurons in female flies is part of a recurrent neural network and drives minutes-long persistent neural activity and persistent social behaviors.
Catherine E Schretter, Yoshinori Aso ... Gerald M Rubin
A discrete group of interconnected neurons are shown to drive aggressive social interactions in Drosophila females and genetic tools to manipulate these neuronal cell types are provided.
Mathematical modelling, together with super-resolution imaging in Arabidopsis, demonstrates that a recently proposed coarsening model for meiotic crossover interference can explain the dynamic patterning of crossovers in many contexts, including in zyp1 and pch2 chromosome structure mutants.
Meghan Laturney, Gabriella R Sterne, Kristin Scott
Postmated increases in sucrose consumption in Drosophila melanogaster females is executed by a female specific circuit that alters neuroendocrine centers to promote hunger.
Luisa F Pallares, Ronan Ledevin ... Sabrina Renaud
An association mapping in wild mice revealed the first candidate loci for within-population molar shape variation and the phenotypic impact of such candidate loci was quantified and validated.
Shristi Pawnikar, Brenda S Magenheimer ... Yinglong Miao
Structural dynamic insights revealed the mechanisms of PC1 activation by stalk-derived peptide agonists which can form a foundation for development of PC1 as a therapeutic target for ADPKD treatment.
Yein Christina Park, Bharat Reddy ... José D Faraldo-Gómez
A theory is presented that explains why some ion channels tend to open in response to membrane stretching, which posits that channel closing is disfavored by the morphological energetics of the lipid bilayer, and increasingly so under lateral tension.
Jeremiah Keyes, Ambhighainath Ganesan ... Jin Zhang
An individual extracellular signal regulates multiple cellular actions through differences in the temporal dynamics of spatially distinct populations of the central signaling enzyme, extracellular-signal regulated kinase.