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    1. Developmental Biology
    2. Neuroscience

    Synapse weakening-induced caspase-3 activity confers specificity to microglia-mediated synapse elimination

    Zhou Yu, Andrian Gutu ... Erin K O’Shea
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Neuroscience
    2. Medicine

    Intrinsic excitation-inhibition imbalance affects medial prefrontal cortex differently in autistic men versus women

    Stavros Trakoshis, Pablo Martínez-Cañada ... Michael V Lombardo
    Excitation-inhibition imbalance affects medial prefrontal cortex differently in autistic males versus females.
    1. Cell Biology
    2. Cancer Biology

    Plectin-mediated cytoskeletal crosstalk as a target for inhibition of hepatocellular carcinoma growth and metastasis

    Zuzana Outla, Gizem Oyman-Eyrilmez ... Martin Gregor
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Evolutionary Biology

    Biases of Principal Component Analysis (PCA) in Physical Anthropology Studies Require a Reevaluation of Evolutionary Insights

    Nima Mohseni, Eran Elhaik
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Neuroscience

    A peptide-neurotensin conjugate that crosses the blood-brain barrier induces pharmacological hypothermia associated with anticonvulsant, neuroprotective and anti-inflammatory properties following status epilepticus in mice

    Lotfi Ferhat, Rabia Soussi ... Michel Khrestchatisky
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
    1. Cell Biology

    Human biallelic MFN2 mutations induce mitochondrial dysfunction, upper body adipose hyperplasia, and suppression of leptin expression

    Nuno Rocha, David A Bulger ... Robert K Semple
    Specific human mitofusin 2 mutations induce selective upper body obesity with suppressed leptin expression and severe adipose mitochondrial dysfunction.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Harnessing AlphaFold to reveal hERG channel conformational state secrets

    Khoa Ngo, Pei-Chi Yang ... Igor Vorobyov
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Neuroscience

    Genetic and pharmacologic alterations of claudin9 levels suffice to induce functional and mature inner hair cells

    Yingying Chen, Jeong Han Lee ... Ebenezer N Yamoah
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Alteration of long and short-term hematopoietic stem cell ratio causes myeloid-biased hematopoiesis

    Katsuyuki Nishi, Taro Sakamaki ... Masanori Miyanishi
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete
    • Inadequate
    1. Neuroscience

    The spatial extent of anatomical connections within the thalamus varies across the cortical hierarchy in humans and macaques

    Amber M. Howell, Shaun Warrington ... Alan Anticevic
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
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