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The coordinated differential modulation of satiety signaling POMC- and hunger signaling AgRP- neurons in the arcuate nucleus of the hypothalamus assigns an important role to noradrenalin to promote feeding.

AGRP neurons integrate environmental food-related cues with internal metabolic signals to modulate interscapular brown adipose tissue thermogenesis and energy expenditure, at least in part, via mTORC1 signalling.

The in vivo transcriptomic fingerprint encoding defective decidualization comprises 120 genes associated with an imbalance hormonal signaling in the decidual endometria of women who developed severe preeclampsia.

A biochemical approach shows that SOX4 guaranteed the PGR protein stability through repressing the ubiquitin E3 ligase HERC4, to make the stroma cell conducive for response to progesterone and decidualization.

A novel neurotrophin signaling axis underpins a behavioral response to food scarcity.

To avoid recognition by the immune system, bacteria use autolysins to trim fragments of peptidoglycans that are exposed on the bacterial cell wall.

Gradual changes in the firing of specific hypothalamic neurons over many hours signal falling energy levels, while short-lived changes over seconds and minutes signal the availability of food.

A specific neuropeptide is responsible for the ability of AgRP neurons to generate long-lasting hunger.

Metabolic stress-induced activation of the JNK3 protein regulates excitatory transmission onto AgRP neurons to regulate food consumption.

Formation and cell pole-localization of chemotactic signaling-arrays is a coupled process mediated by ParP, which drives localized array-assembly and regulates the localization-dynamics of its network constituents.