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128 results found
  1. Episode 52: December 2018

    In this episode, we hear about how flies taste salt, animal personalities, fossil flowers and flying squirrels, and the impact of climate change on seal pups.
    1. Cell Biology
    2. Structural Biology and Molecular Biophysics

    Molecular mechanism for direct actin force-sensing by α-catenin

    Lin Mei et al.
    Biophysical and structural studies reveal how low piconewton forces across actin enhance binding by the critical cell-cell adhesion protein α-catenin versus its force insensitive homolog vinculin.
    1. Evolutionary Biology
    2. Genetics and Genomics

    High social status males experience accelerated epigenetic aging in wild baboons

    Jordan A Anderson et al.
    Among the factors that predict fitness in wild baboons, dominance rank in males, but not in females, is the best predictor of epigenetic aging.
    1. Ecology
    2. Genetics and Genomics

    Social networks predict gut microbiome composition in wild baboons

    Jenny Tung et al.
    Social interactions can have a direct effect on the composition of the gut microbiome in wild primates.
  2. Life story: Chileshe Mabula-Bwalya

    Adjusting to a new identity as a mother comes with challenges, but with help, a rewarding research career is possible.
  3. The participants of ComSciCon 2017

    Communicating freely: ComSciCon

    A workshop series organized by graduate students in the United States aims to help young scientists explain their research to broad and diverse audiences.
    1. Neuroscience

    Different neuronal populations mediate inflammatory pain analgesia by exogenous and endogenous opioids

    Xin-Yan Zhang et al.
    Exogenous opioid analgesia is mediated by MORs expressed in glutamatergic neurons, whereas endogenous opioid analgesia is mediated by MORs expressed in GABAergic neurons.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    E. coli TraR allosterically regulates transcription initiation by altering RNA polymerase conformation

    James Chen et al.
    Cryo-electron microscopy structures, combined with biochemical experiments, show how the E. coli F element-encoded TraR protein regulates transcription initiation by altering RNA polymerase conformation and conformational heterogeneity.
    1. Developmental Biology
    2. Neuroscience

    Purinergic signaling in cochlear supporting cells reduces hair cell excitability by increasing the extracellular space

    Travis A Babola et al.
    Supporting cells in the cochlea change their shape in response to purinergic receptor activation, which influences hair cell excitability by altering potassium redistribution in the extracellular space.

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