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    1. Cell Biology
    2. Genetics and Genomics

    Novel regulators of islet function identified from genetic variation in mouse islet Ca2+ oscillations

    Christopher H Emfinger, Lauren E Clark ... Alan D Attie
    Analysis of islet calcium oscillation responses will provide the field with a resource with which to determine the strain of interest for their specific islet biology questions.
    1. Cancer Biology
    2. Cell Biology

    Cavin3 released from caveolae interacts with BRCA1 to regulate the cellular stress response

    Kerrie-Ann McMahon, David A Stroud ... Robert G Parton
    Cavin3 associates with BRCA1 upon disassembly of caveolae in response to mechanical and non-mechanical stressors to influence DNA repair and apoptosis.
    1. Developmental Biology

    Glycolytic flux-signaling controls mouse embryo mesoderm development

    Hidenobu Miyazawa, Marteinn T Snaebjornsson ... Alexander Aulehla
    The functional link between glycolytic flux, cell signalling and mesoderm patterning is investigated in mouse embryo.
    1. Biochemistry and Chemical Biology

    Acyl-CoA thioesterase-2 facilitates β-oxidation in glycolytic skeletal muscle in a lipid supply dependent manner

    Carmen Bekeova, Ji In Han ... Erin L. Seifert
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Cell Biology

    A remarkable adaptive paradigm of heart performance and protection emerges in response to marked cardiac-specific overexpression of ADCY8

    Kirill V Tarasov, Khalid Chakir ... Edward G Lakatta
    Overexpression of hAC8 engages complex, coordinate adaptation 'circuity' that has evolved in mammalian cells to defend against stress that threatens health or life, and may be important for proper healing in disease states such as heart infarction or failure.
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