A chemical probe was characterized for potency, selectivity, and ability to alter CARM1-dependent epigenetic plasticity against cancer cell invasion.

The three-dimensional architecture of the genome in distinct cell types predicts genes and regulatory elements involved in cell function and disease.

The Hox transcription factor Ultrabithorax (Ubx) represses alternative gene programs during lineage development by lineage-specific Polycomb protein complex retention at Ubx-targeted chromatin sites.

Predicted gene regulatory networks active in planarians adult stem cells provide testable hypotheses about the control of pluripotency and differentiation in animals.

Tools and resources to identify transcriptional regulators that create and maintain differences between photoreceptor subtypes.

Origin recognition complex-associated (ORCA) is crucial for the stability of the Histone H3 lysine 9 methyltransferase megacomplex, which is essential for heterochromatin organization.

The transcriptional activation of the key developmental timer gene, microRNA lin-4, is driven by the transmembrane transcription factor MYRF following its temporally regulated self-cleavage at the cell membrane.

Strategies to enhance Tfh cells for HIV-vaccine antibody persistence and protection is pivotal for vaccine success.