Unveiling a mechanism for the fate decision of B-cell differentiation into two functionally distinct memory B cell subsets.

Post-implantation epiblast maturation and patterning of anterior-posterior axis in mouse embryonic development are mediated by pluripotency transcription factor Zfp281 through transcriptional and epigenetic control of Nodal signaling.

While photoreceptor and bipolar cells exhibit very similar cis-regulatory grammars, subtle differences in homeodomain motif enrichment represent a key distinction driving the divergence in their transcriptomes.

Satellite DNA mediates clustering of multiple chromosomes via formation of chromocenter to encapsulate the full complement of the genome into a single nucleus.

Regenerating neural progenitors of the Xenopus tropicalis tail prioritize differentiation to motor neuron types earlier than proliferation, a decision partly regulated by the transcription factors Pbx3 and Meis1.

A new system to genetically label and manipulate plasma cells in vivo in their microenvironment resolves current technical limitations and reveals tissue-specific homeostatic population turnover.

TCR-mediated downregulation of let-7 microRNAs licenses the differentiation of activated CD8 T cells into cytotoxic T lymphocytes.

The discovery of a mechanism that causes DNA deletions during non-canonical DNA replication termination is described.

The key Target of Rapamycin Complex (TORC1) component Kog1 moves into bodies during glucose starvation to limit reactivation of the complex.

A chemical probe was characterized for potency, selectivity, and ability to alter CARM1-dependent epigenetic plasticity against cancer cell invasion.