4,779 results found
    1. Neuroscience

    Foggy perception slows us down

    Paolo Pretto, Jean-Pierre Bresciani ... Heinrich H Bülthoff
    Virtual reality experiments show that motorists slow down when driving in fog, but they speed up when visibility is reduced equally at all distances.
    1. Chromosomes and Gene Expression

    Non-canonical TAF complexes regulate active promoters in human embryonic stem cells

    Glenn A Maston, Lihua Julie Zhu ... Michael R Green
    The transcription machinery used to regulate gene expression and self-renewal in human embryonic stem cells is different from that found in other cells.
    1. Structural Biology and Molecular Biophysics

    Modelling dynamics in protein crystal structures by ensemble refinement

    B Tom Burnley, Pavel V Afonine ... Piet Gros
    A combination of molecular dynamics simulations and X-ray diffraction data has been used to construct more realistic models of proteins and to provide new insights into their interactions with other proteins and biomolecules.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    KDM2B links the Polycomb Repressive Complex 1 (PRC1) to recognition of CpG islands

    Anca M Farcas, Neil P Blackledge ... Robert J Klose
    A protein that can recognize regions of DNA with a high proportion of unmethylated CpG dinucleotides, and then recruit polycomb group proteins to these CpG islands, has been identified.
    1. Cell Biology
    2. Developmental Biology

    Dual functions of TAF7L in adipocyte differentiation

    Haiying Zhou, Tommy Kaplan ... Robert Tjian
    A combination of cellular, biochemical, genetic and genomic techniques have revealed a new molecular player in the production of fat cells in mice, which could improve our understanding of obesity.
    1. Neuroscience

    Recognition of familiar food activates feeding via an endocrine serotonin signal in Caenorhabditis elegans

    Bo-mi Song, Serge Faumont ... Leon Avery
    The nematode worm C. elegans consumes familiar bacterial species more rapidly than it does novel ones, and this preference for familiarity is mediated by a pair of serotonergic neurons.
    1. Structural Biology and Molecular Biophysics

    Ribosome structures to near-atomic resolution from thirty thousand cryo-EM particles

    Xiao-chen Bai, Israel S Fernandez ... Sjors HW Scheres
    A combination of direct-electron detectors and statistical movie processing allows ribosome cryo-EM structures to be determined to resolutions that were previously only attainable by X-ray crystallography.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Epigenetic conservation at gene regulatory elements revealed by non-methylated DNA profiling in seven vertebrates

    Hannah K Long, David Sims ... Robert J Klose
    Islands of non-methylated DNA are shown to perform a similar epigenetic role in many different vertebrate species.
    1. Structural Biology and Molecular Biophysics

    De novo modeling of the F420-reducing [NiFe]-hydrogenase from a methanogenic archaeon by cryo-electron microscopy

    Deryck J Mills, Stella Vitt ... Janet Vonck
    The structure of a large hydrogenase complex involved in the production of methane by microbes has been determined with cryo-electron microscopy.
    1. Microbiology and Infectious Disease

    Cohabiting family members share microbiota with one another and with their dogs

    Se Jin Song, Christian Lauber ... Rob Knight
    Research on humans and dogs reveals that the communities of microorganisms found on the skin, on the tongue and in the intestine are affected differently by age and cohabitation.

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