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Studies in mice and neurons reveal how modulation of the axonal transport of synaptic vesicles via huntingtin phosphorylation influences the number of vesicles accumulating at the synapse, subsequent glutamate release, and behavior in mice.

Live imaging, transcriptional profiling and mouse models demonstrated that the mesenchyme controls the growth pace but not the mode of branching of the mammary epithelium and unveiled a unique function for Igf1/Igfr1 in embryonic development mammary gland.

Innate lymphoid cells, which are dynamic under steady-state conditions, respond to a colitogenic stimulus by mobilizing from cryptopatches and secreting GM-CSF to organize the pro-inflammatory response.

Human-based electromechanical simulations reveal electrocardiogram biomarkers are better indicators of pro-arrhythmic substrate after myocardial infarction than ejection fraction.

A combined computational, genetic, and biochemical analysis of the hepatitis E virus open reading frame 1 (ORF1) protein identifies a novel domain-domain interaction that is vital for fitness and supports a proposed structural model of the ORF1 polyprotein.

Molecular signals from chloroplasts can synergistically interact with the plant hormone, abscisic acid (ABA), to regulate non-canonical signaling pathways mediating fundamental cellular processes including stomatal closure, seed dormancy and germination.

Identifying 1,907 mitochondrial somatic mutations from 1,675 tumor tissues provides new insights into the causes and effects of the mitochondrial genome mutations found in human cancers.

UNC119 complexes the microtubule binding CRMP to the cortical Ankyrin to immobilize the microtubule cytoskeleton in Caenorhabditis elegans neurons.

Gamma rhythms and representation of visual information in the primary visual cortex are specifically modulated by somatostatin⁺ but not parvalbumin⁺ neurons in reticular thalamic nucleus.

CRISPR/Cas knockout of intraflagellar transport protein 80 shows that this subunit is absolutely required for ciliogenesis, and biophysical studies reveal that this protein may dimerize the intraflagellar transport complex.